Abstract
Wound healing in anastomosed intestine, sutured muscle layer and skin layer was examined as related to the redistribution of zinc during total parenteral nutrition(TPN). Gr.I(normally fed rats) and Gr.II(protein-malnourished rats) received TPN with zinc(Gr.Ia,IIa) or without zinc(Gr.Ib,IIb) for 6 days postoperatively. As a result, there was no significant difference between Gr.Ia and Ib in bursting pressure of intestinal anastomosis, tensile strength(TS) of muscle wound and skin wound, collagen-hydroxyproline (HYP) in each wound and zinc concentration in each tissue, whereas, the reduction of TS and HYP in skin wound was marked in Gr.IIb compared to Gr.IIa accompanied with the decrease of skin zinc concentration. In conclusion, redistribution of zinc was manifested in protein-malnourished rats during TPN and it might affect wound healing.
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© 1990 Springer-Verlag Tokyo
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Nezu, R., Takagi, Y., Okada, A., Kawashima, Y. (1990). Effect of Zinc Redistribution on Wound Healing during Total Parenteral Nutrition in Rats. In: Tomita, H. (eds) Trace Elements in Clinical Medicine. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68120-5_28
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DOI: https://doi.org/10.1007/978-4-431-68120-5_28
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68122-9
Online ISBN: 978-4-431-68120-5
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