Summary
A total of 118 patients with osteosarcoma underwent operation at the Orthopaedic University Clinic from 1976 until 1986. There were 57 female and 61 male patients with an age of 20.2 ± 11.9 years in the female and 19.5 ± 9.7 in the male group. In 25 cases, amputation was performed, of which 13 were above the knee. Resectional therapy was carried out in 93 cases, 49 of them with tumors in the distal femur, 14 in the proximal tibia, and 13 in the proximal humerus; there were 17 at other locations.
Twenty-six cases underwent resection and reconstruction as rotationplasty; in 49 cases a tumor endoprosthesis was implanted. Nine cases had a bone graft reconstruction; no reconstruction was necessary in nine. The distribution of endoprostheses was: 23 in the femur, 15 in the humerus, and 11 in the tibia. The radicality of surgery was investigated and it was seen to be wide and radical in 104 cases (88.2%). In 14 cases, marginal or intralesional surgery was done (11.8%), and this influenced the end result. Amputation and rotationplasty as the more aggressive therapy was compared with resection with or without an endoprosthesis but preserving the full length of the extremity.
The 3-year survival in 68 cases with a minimum follow-up of 3 years showed 72% in the group with amputation and rotationplasty (32 cases) and 75% in the group with resection and resection with an endoprosthesis (36 cases). Therefore, no influence on the long-term survival was seen in limb-preserving surgery versus amputation and rotationplasty.
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© 1989 Springer-Verlag Tokyo
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Kotz, R. et al. (1989). Surgical Margins Influencing Oncological Results in Osteosarcoma. In: Yamamuro, T. (eds) New Developments for Limb Salvage in Musculoskeletal Tumors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68072-7_13
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DOI: https://doi.org/10.1007/978-4-431-68072-7_13
Publisher Name: Springer, Tokyo
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