Imidacloprid (Figure 1) is the first active ingredient of the chemical class of nicotinoid insecticides to reach the market. Toxicological information on this class of substances is nearly nonexistent in open literature. Only limited toxicological information on the structurally related compound nitroguanidine is available, and it indicates no critical toxicological properties (GRA & 11986–1990).


Good Laboratory Practice Nerve Termin Body Weight Gain Reduction Toxicological Information Maternal Toxicity 
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Copyright information

© Springer Japan 1999

Authors and Affiliations

  • J. Thyssen
    • 1
  • L. Machemer
    • 2
  1. 1.Agriculture DivisionToxicology, Bayer CorporationStillwell, KansasUSA
  2. 2.Bayer AG, BG HealthInstitute of ToxicologyWuppertalGermany

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