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Heart Replacement pp 159–166Cite as

Mechanical Circulatory Support as a Bridge to Transplantation: Berlin Experience in 154 Patients

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Abstract

Circulatory support with an artificial heart provides a valuable supplement in the field of heart transplantation. An artificial heart can be implanted before a suitable donor organ is available, or after heart transplantation if unmanageable acute graft rejection or insufficiency develops. The so-called bridge procedure, i.e., artificial heart support followed by heart transplantation, was introduced by Cooley in 1969 with the use of the Liotta total artificial heart (TAH) [1]. Thirteen years later, the Jarvik-7 (Symbion, Salt Lake City, UT, USA) TAH was permanently implanted in a human for the first time by DeVries et al. [2]. Although initially all of the TAH recipients died of multiple complications, close examination of the results provided many cautionary lessons for the clinical use of artificial hearts. The first successful bridging was performed in 1984 by Starnes et al. [3], who used an implantable Novacor (Baxter Healthcare, Novacor Division, Oakland, CA, USA) left ventricular assist device (LVAD), followed by Hill et al. [4] with a Pierce-Donachy LVAD, and in 1985 by Copeland et al. [5] with a Jarvik-7 TAH. During the ensuing decade, the bridge-to-transplantation procedure spread all over the world with increasing success.

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References

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Author information

Authors and Affiliations

  1. Department of Thoracic and Cardiovascular Surgery, German Heart Institute Berlin, Augustenburger Platz 1, 13353, Berlin, Germany

    Kozo Ishino, Arnulf Schiessler, Yuguo Weng, Matthias Loebe, Gabriele Arndt, Ewald Hennig & Roland Hetzer

Authors
  1. Kozo Ishino
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  2. Arnulf Schiessler
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  3. Yuguo Weng
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  4. Matthias Loebe
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  5. Gabriele Arndt
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  6. Ewald Hennig
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  7. Roland Hetzer
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Editor information

Editors and Affiliations

  1. Shonan Center, Terumo Corporation, 1500 Inokuchi, Naka-machi, Ashigarakami-gun, 259-01, Kanagawa, Japan

    Tetsuzo Akutsu M.D., Ph.D. (Chairman of the Board of Directors) (Chairman of the Board of Directors)

  2. Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women’s Medical College, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162, Japan

    Hitoshi Koyanagi M.D. (Chairman and Professor) (Chairman and Professor)

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© 1996 Springer Japan

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Ishino, K. et al. (1996). Mechanical Circulatory Support as a Bridge to Transplantation: Berlin Experience in 154 Patients. In: Akutsu, T., Koyanagi, H. (eds) Heart Replacement. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67020-9_20

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  • DOI: https://doi.org/10.1007/978-4-431-67020-9_20

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-67022-3

  • Online ISBN: 978-4-431-67020-9

  • eBook Packages: Springer Book Archive

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