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Inhibition of M-Type K+ currents by Cognition Enhancers in NG108-15 Cells and Rat Cerebral Neurons in Culture

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Abstract

The electrophysiological effects of KST-5452, an ml muscarinic acetylcholine receptor (AChR) binding compound (Kishida et al. 1994), and linopirdine, a neurotransmitter release enhancer (Aiken et al. 1996; Nickolson et al. 1990) were studied in NG108-15 neuroblastoma x glioma hybrid cells transfected with ml-muscarinic AChR cDNA, using either the conventional whole-cell or the nystatin perforated-patch recording mode under voltage-clamp conditions.

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References

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© 2000 Springer Japan

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Noda, M., Higashida, H., Akaike, N. (2000). Inhibition of M-Type K+ currents by Cognition Enhancers in NG108-15 Cells and Rat Cerebral Neurons in Culture. In: Kuba, K., Higashida, H., Brown, D.A., Yoshioka, T. (eds) Slow Synaptic Responses and Modulation. Springer, Tokyo. https://doi.org/10.1007/978-4-431-66973-9_6

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  • DOI: https://doi.org/10.1007/978-4-431-66973-9_6

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-66975-3

  • Online ISBN: 978-4-431-66973-9

  • eBook Packages: Springer Book Archive

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