Summary
A new implantable rotary blood pump (the diagonal pump) was tested. Hemodynamic performance and organ perfusion were analyzed in a heart failure model and compared to the performance of a pulsatile assist device (Medos, Aachen, Germany). Six sheep were instrumented with a. 50 Fr. left atrial inflow cannula and a 16-mm Dacron outflow graft to the descending aorta. After control measurements, left ventricular heart failure was induced by intracoronary injection of microspheres. Measurements were repeated during heart failure, during mechanical support with the Medos device, and during support with the new rotary blood pump. Organ perfusion was analyzed by injection of colored microspheres. Cardiac output, arterial blood pressure, left and right atrial pressure, and first derivative of the left ventricular pressure were all significantly changed during heart failure. These parameters were restored by both types of mechanical support to exactly the same level. Organ perfusion was significantly reduced in all organs during heart failure. There was no difference in organ perfusion with the diagonal pump compared with the pulsatile Medos device. Hemodynamic status and organ perfusion due to left ventricular failure are restored in exactly the same way by a nonpulsatile miniature rotary blood pump and a pneumatic pulsatile assist device (Medos). Rotary blood pumps can be miniaturized and are therefore more attractive than pulsatile displacement pumps for long-term mechanical support.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Meyns BP, Sergeant PT, Daenen WJ, Flameng WJ (1995) Left ventricular assistance with the transthoracic 24F Hemopump for recovery of the failing heart. Ann Thorac Surg 60:392–397
Frazier OH, Rose EA, Macmanus Q, Burton NA, Lefrak EA, Poirier VL, Dasse KA (1992) Multicenter clinical evaluation of the Heartmate 1000 IP left ventricular assist device. Ann Thorac Surg 53:1080–1090
Dew MA, Kormos RL, Roth LH, Armitage JM, Pristas JM, Harris RC, Capretta C, Griffith BP (1993) Life quality in the era of bridging to cardiac transplantation. ASAIO J 39:145–152
Ohtsubo S, Nosé Y (1996) Evolution towards the development of totally implantable rotary blood pumps. Artif Organs 20:461–462
Nosé Y, Kawahito K, Nakazawa T (1996) Can we develop a nonpulsatile permanent rotary blood pump? Yes, we can. Artif Organs 20:467–474
Nosé Y (1993) Nonpulsatile mode of blood flow required for cardiopulmonary bypass and total body perfusion. Artif Organs 17:92–102
Kowallik P, Schultz R, Guth BD, Schade A, Paffhausen W, Gross R, Heusch G (1991) Measurement of regional myocardial blood flow with multiple colored microspheres. Circulation 83:974–982
Rudolph AM, Heymann MA (1967) The circulation of the fetus in utero: Methods of studying distribution of blood flow, cardiac output and organ blood flow. Circ Res 21:163–184
Wieland W, Wouters PF, Van Aken H, Flameng W (1993) Measurement of organ blood flow with coloured microspheres: a first time-saving improvement using automated spectophotometry. Proc Comp Cardiol 9:691–694
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer-Verlag Tokyo
About this paper
Cite this paper
Meyns, B. et al. (1998). Implantable Rotary Blood Pump Performs as Well as Pulsatile Pneumatic Assist Device. In: Akutsu, T., Koyanagi, H. (eds) Heart Replacement. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65921-1_68
Download citation
DOI: https://doi.org/10.1007/978-4-431-65921-1_68
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-65923-5
Online ISBN: 978-4-431-65921-1
eBook Packages: Springer Book Archive