Summary
The major histocompatibility complex (MHC) is a genomic region that has for many years interested immunologists, population geneticists, and evolutionary biologists (Klein 1986). Here we present a hypothesis regarding the evolution of this chromosomal region and a strategy that we have developed to test this hypothesis.
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© 2000 Springer Japan
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Rached, L.A., Pontarotti, P. (2000). The MHC « Big-Bang » : duplication and exon shuffling during chordate evolution. A hypothetico-deductive approach. In: Kasahara, M. (eds) Major Histocompatibility Complex. Springer, Tokyo. https://doi.org/10.1007/978-4-431-65868-9_3
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DOI: https://doi.org/10.1007/978-4-431-65868-9_3
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-65870-2
Online ISBN: 978-4-431-65868-9
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