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Related Topic: Liposomes—Recent Advances and Future Perspective

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Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds

Abstract

The skin has been used as an administration route for medicine for many years. When the transdermal application of a compound is considered, it is difficult to deliver it inside the body through the stratum corneum. Therefore, many researchers have examined the percutaneous penetration-enhancing method. One method using liposomes has been considered. Liposomes can function not only as a transdermal absorption enhancement method but also as a controlled-release method.

Recently, new types of liposomes that include non-ionic detergent or ethanol in the membrane are gaining attention, as are phospholipid liposomes. These new vehicles are called elastic liposomes, and are promising candidates for new strategies to enhance the effectiveness of percutaneously applied compounds. Here we review recent advances and future perspectives of liposomes as percutaneous drug carriers.

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Correspondence to Yoshihiro Tokudome .

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Yokota, M., Tokudome, Y. (2017). Related Topic: Liposomes—Recent Advances and Future Perspective. In: Sugibayashi, K. (eds) Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer, Tokyo. https://doi.org/10.1007/978-4-431-56526-0_11

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