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Recent Topics in the Epidemiology of Kawasaki Disease

  • Ritei UeharaEmail author
Chapter

Abstract

The incidence rates of Kawasaki disease (KD) in Northeast Asians are almost 20 times those of whites. Incidence is higher among Japanese Americans than among other Asian Americans living in Hawaii, which indicates that genetic factors rather than environmental factors have the predominant role in the occurrence of KD in these populations. Approximately 10–15 % of KD patients have persistent or recrudescent fever more than 36 h after the end of initial intravenous immunoglobulin infusion. KD is uncommon in adults, although the prevalences of specific diagnostic criteria are roughly similar in adults and children. The prevalence of coronary aneurysms is lower in adults than in children. Dr. Kawasaki saw the first case of typical KD in 1961. After he treated several more similar cases, the first epidemiologic survey of KD was conducted in 1970.

Keywords

Epidemiology Incidence Immunoglobulin Adult 

References

  1. 1.
    Nakamura Y, Yashiro M, Uehara R, Sadakane A, Tsuboi S, Aoyama Y, et al. Epidemiologic features of Kawasaki disease in Japan: results of the 2009–2010 nationwide survey. J Epidemiol. 2012;22(3):216–21. http://dx.doi.org/10.2188/jea.JE20110126 PMID:22447211.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Uehara R, Belay ED. Epidemiology of Kawasaki disease in Asia, Europe, and the United States. J Epidemiol. 2012;22(2):79–85. http://dx.doi.org/10.2188/jea.JE20110131 PMID:22307434.CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Yim D, Curtis N, Cheung M, Burgner D. Update on Kawasaki disease: epidemiology, aetiology and pathogenesis. J Paediatr Child Health. 2013;49(9):704–8. http://dx.doi.org/10.1111/jpc.12172 PMID:23560706.CrossRefPubMedGoogle Scholar
  4. 4.
    Yim D, Curtis N, Cheung M, Burgner D. An update on Kawasaki disease II: clinical features, diagnosis, treatment and outcomes. J Paediatr Child Health. 2013;49(8):614–23. http://dx.doi.org/10.1111/jpc.12221 PMID:23647873.CrossRefPubMedGoogle Scholar
  5. 5.
    Bayers S, Shulman ST, Paller AS. Kawasaki disease: part II. Complications and treatment. J Am Acad Dermatol. 2013;69(4):513 e1–8. http://dx.doi.org/10.1016/j.jaad.2013.06.040.CrossRefPubMedGoogle Scholar
  6. 6.
    Sève P, Stankovic K, Smail A, Durand DV, Marchand G, Broussolle C. Adult Kawasaki disease: report of two cases and literature review. Semin Arthritis Rheum. 2005;34(6):785–92. http://dx.doi.org/10.1016/j.semarthrit.2005.01.012 PMID:15942913.CrossRefPubMedGoogle Scholar
  7. 7.
    Gomard-Mennesson E, Landron C, Dauphin C, Epaulard O, Petit C, Green L, et al. Kawasaki disease in adults: report of 10 cases. Medicine (Baltimore). 2010;89(3):149–58. http://dx.doi.org/10.1097/MD.0b013e3181df193c PMID:20453601.CrossRefGoogle Scholar
  8. 8.
    Kawasaki T, Naoe S. History of Kawasaki disease. Clin Exp Nephrol. 2014;18(2):301–4. http://dx.doi.org/10.1007/s10157-013-0877-6 PMID:24595558.CrossRefPubMedGoogle Scholar
  9. 9.
    Burns JC, Kushner HI, Bastian JF, Shike H, Shimizu C, Matsubara T, et al. Kawasaki disease: a brief history. Pediatrics. 2000;106(2), E27. http://dx.doi.org/10.1542/peds.106.2.e27 PMID:10920183.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Japan 2017

Authors and Affiliations

  1. 1.Utsunomiya City Public Health CenterUtsunomiya CityJapan

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