Embryo Cryopreservation in Breast Cancer Patients

  • Giuliano Bedoschi
  • Kutluk OktayEmail author


Breast cancer is the second most common type of cancer expected to occur in women in 2014, accounting for 29 % of incident cases among women. Approximately 11 % of all breast cancer cases occur in women <45 years. Most of those patients are likely to undergo adjuvant systemic chemotherapy with a significant impact on ovarian reserve and future reproductive potential. Embryo cryopreservation is the most established technique for fertility preservation. This procedure is an attractive strategy for fertility preservation in reproductive age breast cancer patients with available partner or willing to use donor semen. Some special considerations should be given to ovarian stimulation for fertility preservation in breast cancer patients. The development of ovarian stimulation protocols using aromatase inhibitor combined with gonadotropin appears to be effective and safe for breast cancer patients. In this chapter, we will appraise and summarize the current state of embryo cryopreservation in breast cancer patients in order to provide a better understanding of the efficacy and safety of this fertility preservation technique.


Embryo cryopreservation Breast cancer Fertility preservation Ovarian stimulation Letrozole 


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Copyright information

© Springer Japan 2016

Authors and Affiliations

  1. 1.New York Medical CollegeValhallaUSA
  2. 2.Innovation Institute for Fertility Preservation and In Vitro FertilizationNew YorkUSA

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