Risk of Transferring Malignant Cells with Transplanted Frozen-Thawed Ovarian Tissue

  • Marie-Madeleine DolmansEmail author
  • Michelle Soares


Although ovarian tissue cryopreservation and transplantation have emerged as a real option to preserve and restore fertility in young cancer patients, there is a legitimate concern regarding the possible presence of malignant cells in the ovarian tissue, which could lead to recurrence of the disease after reimplantation. The present chapter reviews the existing literature on the subject to evaluate the risk of transplanting malignant cells in case of the main malignant indications for ovarian tissue cryopreservation.


Ovarian tissue cryopreservation Ovarian tissue transplantation Cancer Risks Malignant cells 



The authors thank Mira Hryniuk, B.A., for reviewing the English language of the manuscript.


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Copyright information

© Springer Japan 2016

Authors and Affiliations

  1. 1.Pôle de Recherche en Gynécologie, Institut de Recherche Expérimentale et Clinique (IREC)Cliniques Universitaires Saint LucBrusselsBelgium
  2. 2.Département de GynécologieCliniques Universitaires Saint-LucBrusselsBelgium

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