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Optogenetics pp 89-107 | Cite as

Color Tuning in Retinylidene Proteins

  • Kota Katayama
  • Sivakumar Sekharan
  • Yuki SudoEmail author

Abstract

Retinylidene proteins (also called rhodopsins) are membrane-embedded photoreceptors that contain a vitamin A aldehyde linked to a lysine residue by a Schiff base as their light-sensing chromophore. The chromophore is surrounded by seven-transmembrane α-helices and absorbs light at different wavelengths due to differences in the electronic energy gap between its ground and excited states. The variation in the wavelength of maximal absorption (λmax: 360–620 nm) of rhodopsins arises due to interaction between the apoprotein (opsin) and the retinyl chromophore, the ‘opsin shift’. This chapter reviews the color tuning mechanisms in type-1 microbial and type-2 animal rhodopsins as revealed mainly by our experimental and theoretical studies.

Keywords

Retinal Color tuning Rhodopsin π-conjugation Color variant Visible light Water molecule Vitamin-A 

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Copyright information

© Springer Japan 2015

Authors and Affiliations

  1. 1.Department of Frontier MaterialsNagoya Institute of TechnologyNagoyaJapan
  2. 2.Department of ChemistryYale UniversityNew HavenUSA
  3. 3.Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical SciencesOkayama UniversityOkayamaJapan

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