Testing Cognition and Rehabilitation in Unilateral Neglect with Wedge Prism Adaptation: Multiple Interplays Between Sensorimotor Adaptation and Spatial Cognition

  • Yves Rossetti
  • Sophie Jacquin-Courtois
  • Marco Calabria
  • Carine Michel
  • Shaun Gallagher
  • Jacques Honoré
  • Jacques Luauté
  • Alessandro Farné
  • Laure Pisella
  • Gilles Rode
Chapter

Abstract

Spatial neglect is a neurological condition characterised by deficits for perceiving, attending, representing, and/or performing actions within their left-sided space, responsible for numerous debilitating effects in everyday life, for poor functional recovery, and for decreased ability to benefit from treatment. Exposure to a right lateral displacement of the visual field (induced by a simple target-pointing task with base-left wedge prisms) is known to directionally bias visuomotor coordination and can be compensated by both sensorimotor adaptation and cognitive processes. Sensorimotor adaptation gives rise to after-effects whose duration is amplified in neglect patients and has been repeatedly shown to improve most neglect symptoms. Interestingly the effectiveness of PA has also been demonstrated for non-motor and non-visual tasks, such as for somatosensory extinction, for deficits in mental imagery of geographic maps and in number bisection, and even for visuo-constructive disorders, i.e. for unexposed sensory and motor modalities. Visuomotor adaptation appears to interact with higher-order brain functions related to multisensory integration and can have beneficial effects on sensory processing in different modalities as well as cognition. The bottom-up effects of prism adaptation on spatial cognition can also be applied to patients with complex regional pain syndrome who exhibit a spatial cognition bias towards the affected side. Such bottom-up effects exemplify the powerful potential of new approaches to rehabilitation that rely on physiological grounds and bypass intentional control, resulting in reduced attentional cost. We speculate that bottom-up effects may be completed by rounds of reverberation forming a virtuous circle leading to full-blown therapeutic effects.

Keywords

Bottom-up rehabilitation Chronic regional pain syndrome (CRPS) Prism adaptation Spatial cognition Spatial neglect 

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Copyright information

© Springer Japan 2015

Authors and Affiliations

  • Yves Rossetti
    • 1
    • 2
  • Sophie Jacquin-Courtois
    • 1
    • 2
  • Marco Calabria
    • 1
    • 3
  • Carine Michel
    • 4
  • Shaun Gallagher
    • 5
  • Jacques Honoré
    • 1
  • Jacques Luauté
    • 1
    • 2
  • Alessandro Farné
    • 1
  • Laure Pisella
    • 1
  • Gilles Rode
    • 1
    • 2
  1. 1.Centre de Recherche en Neurosciences de Lyon, ImpAct team, Inserm, CNRS, Université de LyonBronFrance
  2. 2.Hospices Civils de Lyon, Service de Médecine Physique et Réadaptation Neurologique, Plate-forme Mouvement et HandicapHôpital Henry GabrielleLavalFrance
  3. 3.Universitat Pompeu FabraBarcelonaSpain
  4. 4.INSERM U1093 Cognition, Action, et Plasticité Sensorimotrice Université de BourgogneDijon cedexFrance
  5. 5.Department of PhilosophyUniversity of MemphisMemphisUSA

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