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ECD for Kidney Transplantation

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Marginal Donors

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Abstract

Because of the shortage of organs for kidney transplantation, there has been greater interest in recent years in the use of expanded criteria donors (ECDs), defined as brain-dead donors aged ³60 years or donors aged ³50 years with a history of hypertension plus terminal donor serum creatinine £1.5mg/dL, or death resulting from a cerebrovascular accident. Although long-term outcomes of ECD kidneys has been worse than that of standard-criteria donor kidneys, mortality is decreased with ECD kidney transplant compared with remaining on dialysis therapy. This review focuses on the use of ECDs to define donor and recipient selection criteria, including the usefulness of donor kidney biopsies as a pretransplant test for dual kidney transplantation. In addition, short- and long-term survival for younger and older patients who received ECD kidney transplantation compared with remaining on dialysis therapy is reviewed.

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Authors and Affiliations

  1. Division for Innovative Surgery and Transplantation, National Center for Child Health and Development, 2-10-1 Okura, Setagayaku, Tokyo, 157-8535, Japan

    Naoto Matsuno

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  1. Naoto Matsuno
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Correspondence to Naoto Matsuno .

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Editors and Affiliations

  1. Department of Surgery and Clinical Research Center, Chiba-East National Hospital,, Chiba, Japan

    Takehide Asano

  2. Department of Therapeutics for End-Stage Organ Dysfunction, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

    Norihide Fukushima

  3. Department of Organ Transplant Surgery, Fujita Health University, Aichi, Japan

    Takashi Kenmochi

  4. Division for Innovative Surgery and Transplantation, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan

    Naoto Matsuno

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© 2014 Springer Japan

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Matsuno, N. (2014). ECD for Kidney Transplantation. In: Asano, T., Fukushima, N., Kenmochi, T., Matsuno, N. (eds) Marginal Donors. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54484-5_16

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  • DOI: https://doi.org/10.1007/978-4-431-54484-5_16

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54483-8

  • Online ISBN: 978-4-431-54484-5

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