Abstract
Despite marked advances in cardiovascular surgery and perioperative management, children with congenital heart disease still experience many problems in their adult life. One of the issues that should be resolved is progressive heart failure toward adolescence. During cardiac catheterization, the parameters of cardiac function and vascular function, according to which the best strategy for patients could be chosen, are obtained. These data are useful for elucidating the hemodynamic features of specific structural heart disease and could clarify the mechanisms of heart failure even in children. However, vascular function tends to be overlooked as a factor for worsening heart failure in view of the long term, and only a few comprehensive reviews are available in the field of congenital heart disease.
This chapter summarizes the currently available methods for evaluating vascular function, especially based on catheterization laboratory examination in children. The first part of this chapter discusses the direct and load-independent arterial characteristics of vessels, which provide convincing information for clinical study and for predicting hemodynamic changes corresponding to changes in loading status. In the latter part, indirect evaluation of vessels is presented, which can be useful in real-time decision making in a catheterization laboratory. Last, we also discuss the venous and minor vessel functions that can affect organ congestion and dysfunction.
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References
Kass DA (2005) Ventricular arterial stiffening: integrating the pathophysiology. Hypertension 46:185–193
Chen CH, Nakayama M, Nevo E, Fetics BJ, Maughan WL, Kass DA (1998) Coupled systolic-ventricular and vascular stiffening with age: implications for pressure regulation and cardiac reserve in the elderly. J Am Coll Cardiol 32:1221–1227
Kelly RP, Ting CT, Yang TM et al (1992) Effective arterial elastance as index of arterial vascular load in humans. Circulation 86:513–521
Ronco C, Cicoira M, McCullough PA (2012) Cardiorenal syndrome type 1: pathophysiological crosstalk leading to combined heart and kidney dysfunction in the setting of acutely decompensated heart failure. J Am Coll Cardiol 60:1031–1042
Verbrugge FH, Dupont M, Steels P et al (2013) Abdominal contributions to cardiorenal dysfunction in congestive heart failure. J Am Coll Cardiol 62:485–495
Aronson D, Abassi Z, Allon E, Burger AJ (2013) Fluid loss, venous congestion, and worsening renal function in acute decompensated heart failure. Eur J Heart Fail 15:637–643
Moller S, Bernardi M (2013) Interactions of the heart and the liver. Eur Heart J 34:2804–2811
Price JF, Mott AR, Dickerson HA et al (2008) Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome? Pediatr Crit Care Med 9:279–284
Butera G, Marini D, MacDonald ST (2011) Protein-losing enteropathy resolved by percutaneous intervention. Catheter Cardiovasc Interv 78:584–588
Ou P, Celermajer DS, Jolivet O et al (2008) Increased central aortic stiffness and left ventricular mass in normotensive young subjects after successful coarctation repair. Am Heart J 155:187–193
Trojnarska O, Mizia-Stec K, Gabriel M et al (2011) Parameters of arterial function and structure in adult patients after coarctation repair. Heart Vessels 26:414–420
Saiki H, Kojima T, Seki M, Masutani S, Senzaki H (2012) Marked disparity in mechanical wall properties between ascending and descending aorta in patients with tetralogy of Fallot. Eur J Cardiothorac Surg 41:570–573
Seki M, Kurishima C, Kawasaki H, Masutani S, Senzaki H (2012) Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal aortic mechanical property. Eur J Cardiothorac Surg 41:277–282
Senzaki H, Iwamoto Y, Ishido H et al (2008) Arterial haemodynamics in patients after repair of tetralogy of Fallot: influence on left ventricular after load and aortic dilatation. Heart 94:70–74
Senzaki H, Chen CH, Ishido H et al (2005) Arterial hemodynamics in patients after Kawasaki disease. Circulation 111:2119–2125
Mansour AS, Yannoutsos A, Majahalme N et al (2013) Aortic stiffness and cardiovascular risk in type 2 diabetes. J Hypertens 31:1584–1592
Mitchell GF, Hwang SJ, Vasan RS et al (2010) Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation 121:505–511
Sunagawa K, Maughan WL, Sagawa K (1985) Stroke volume effect of changing arterial input impedance over selected frequency ranges. Am J Physiol 248:H477–H484
Levy BI, Michel JB, Salzmann JL et al (1988) Effects of chronic inhibition of converting enzyme on mechanical and structural properties of arteries in rat renovascular hypertension. Circ Res 63:227–239
Huijberts MS, Wolffenbuttel BH, Boudier HA et al (1993) Aminoguanidine treatment increases elasticity and decreases fluid filtration of large arteries from diabetic rats. J Clin Invest 92:1407–1411
Dujardin JP, Stone DN (1981) Characteristic impedance of the proximal aorta determined in the time and frequency domain: a comparison. Med Biol Eng Comput 19:565–568
O’Rourke MF, Avolio AP (1980) Pulsatile flow and pressure in human systemic arteries. Studies in man and in a multibranched model of the human systemic arterial tree. Circ Res 46:363–372
O’Rourke MF, Nichols WW (2005) Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension 45:652–658
Laskey WK, Kussmaul WG, Martin JL, Kleaveland JP, Hirshfeld JW Jr, Shroff S (1985) Characteristics of vascular hydraulic load in patients with heart failure. Circulation 72:61–71
Stergiopulos N, Meister JJ, Westerhof N (1995) Evaluation of methods for estimation of total arterial compliance. Am J Physiol 268:H1540–H1548
Stergiopulos N, Westerhof BE, Westerhof N (1999) Total arterial inertance as the fourth element of the windkessel model. Am J Physiol 276:H81–H88
Schiffrin EL (2004) Vascular stiffening and arterial compliance. Implications for systolic blood pressure. Am J Hypertens 17:39S–48S
Chemla D, Nitenberg A, Teboul JL et al (2008) Subendocardial viability ratio estimated by arterial tonometry: a critical evaluation in elderly hypertensive patients with increased aortic stiffness. Clin Exp Pharmacol Physiol 35:909–915
Liu Z, Brin KP, Yin FC (1986) Estimation of total arterial compliance: an improved method and evaluation of current methods. Am J Physiol 251:H588–H600
Chemla D, Hebert JL, Coirault C et al (1998) Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans. Am J Physiol 274:H500–H505
Saito M, Okayama H, Nishimura K et al (2008) Possible link between large artery stiffness and coronary flow velocity reserve. Heart 94:e20
Niwa K, Perloff JK, Bhuta SM et al (2001) Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses. Circulation 103:393–400
Niwa K, Siu SC, Webb GD, Gatzoulis MA (2002) Progressive aortic root dilatation in adults late after repair of tetralogy of Fallot. Circulation 106:1374–1378
Alexander J Jr, Burkhoff D, Schipke J, Sagawa K (1989) Influence of mean pressure on aortic impedance and reflections in the systemic arterial system. Am J Physiol 257:H969–H978
Westerhof N, Westerhof BE (2013) A review of methods to determine the functional arterial parameters stiffness and resistance. J Hypertens 31:1769–1775
Mitchell GF, Lacourciere Y, Ouellet JP et al (2003) Determinants of elevated pulse pressure in middle-aged and older subjects with uncomplicated systolic hypertension: the role of proximal aortic diameter and the aortic pressure-flow relationship. Circulation 108:1592–1598
Murgo JP, Westerhof N, Giolma JP, Altobelli SA (1980) Aortic input impedance in normal man: relationship to pressure wave forms. Circulation 62:105–116
Wald RM, Redington AN, Pereira A et al (2009) Refining the assessment of pulmonary regurgitation in adults after tetralogy of Fallot repair: should we be measuring regurgitant fraction or regurgitant volume? Eur Heart J 30:356–361
Romeih S, Groenink M, van der Plas MN et al (2012) Effect of age on exercise capacity and cardiac reserve in patients with pulmonary atresia with intact ventricular septum after biventricular repair. Eur J Cardiothorac Surg 42:50–55
Hidaka N, Sugitani M, Fujita Y, Fukushima K, Tsukimori K, Wake N (2009) Preload index of the inferior vena cava as a possible predictive marker of hydropic changes in fetuses with Ebstein anomaly. J Ultrasound Med 28:1369–1374
Senzaki H, Masutani S, Ishido H et al (2006) Cardiac rest and reserve function in patients with Fontan circulation. J Am Coll Cardiol 47:2528–2535
Guyton AC (1955) Determination of cardiac output by equating venous return curves with cardiac response curves. Physiol Rev 35:123–129
Guyton AC, Adkins LH (1954) Quantitative aspects of the collapse factor in relation to venous return. Am J Physiol 177:523–527
Guyton AC, Lindsey AW, Abernathy B, Richardson T (1957) Venous return at various right atrial pressures and the normal venous return curve. Am J Physiol 189:609–615
Beard DA, Feigl EO (2011) Understanding Guyton’s venous return curves. Am J Physiol Heart Circ Physiol 301:H629–H633
Mace L, Dervanian P, Bourriez A et al (2000) Changes in venous return parameters associated with univentricular Fontan circulations. Am J Physiol Heart Circ Physiol 279:H2335–H2343
Imai Y, Ito H, Minatoguchi S et al (1992) The effects of phentolamine and nitroglycerin on right-sided hemodynamics in cardiac patients can be explained by a shift of the systemic venous return curve and right-ventricular output curve. Jpn Circ J 56:801–814
Ohte N, Narita H, Sugawara M et al (2003) Clinical usefulness of carotid arterial wave intensity in assessing left ventricular systolic and early diastolic performance. Heart Vessels 18:107–111
Niki K, Sugawara M, Chang D et al (2002) A new noninvasive measurement system for wave intensity: evaluation of carotid arterial wave intensity and reproducibility. Heart Vessels 17:12–21
Bleasdale RA, Mumford CE, Campbell RI, Fraser AG, Jones CJ, Frenneaux MP (2003) Wave intensity analysis from the common carotid artery: a new noninvasive index of cerebral vasomotor tone. Heart Vessels 18:202–206
Zambanini A, Cunningham SL, Parker KH, Khir AW, Mc GTSA, Hughes AD (2005) Wave-energy patterns in carotid, brachial, and radial arteries: a noninvasive approach using wave-intensity analysis. Am J Physiol 289:H270–H276
Parker KH, Jones CJ (1990) Forward and backward running waves in the arteries: analysis using the method of characteristics. J Biomech Eng 112:322–326
Saiki H, Kurishima C, Masutani S, Senzaki H (2014) Cerebral circulation in patients with Fontan circulation: assessment by carotid arterial wave intensity and stiffness. Ann Thorac Surg 97:1394–1399
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Saiki, H., Senzaki, H. (2015). Assessment of Vascular Function by Using Cardiac Catheterization. In: Senzaki, H., Yasukochi, S. (eds) Congenital Heart Disease. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54355-8_6
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DOI: https://doi.org/10.1007/978-4-431-54355-8_6
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