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CQ28. Do Total Thyroidectomy and Lymph Node Dissection for Sporadic and Hereditary Medullary Carcinoma Improve the Prognosis?

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Treatment of Thyroid Tumor

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Abstract

Whether the extent of thyroidectomy or the execution and the extent of lymph node dissection affect the prognosis of patients with medullary carcinoma was investigated. Hereditary and sporadic medullary carcinomas were separately investigated.

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References

  1. Miyazawa Y, Sakata H, Kawashima T et al (2004) (Text in Japanese) Rinsho Geka 59:413–417 [Case Series (CS)]

    Google Scholar 

  2. Iihara M, Yamashita T, Okamoto T et al (1997) A nationwide clinical survey of patients with multiple endocrine neoplasia type 2 and familial medullary thyroid carcinoma in Japan. Jpn J Clin Oncol 27:128–134 (CS)

    Article  PubMed  CAS  Google Scholar 

  3. Kebebew E, Ituarte PH, Siperstein AE et al (2000) Medullary thyroid carcinoma: clinical characteristics, treatment, prognostic factors, and a comparison of staging systems. Cancer 88:1139–1148 (RS)

    Article  PubMed  CAS  Google Scholar 

  4. Miyauchi A, Matsuzuka F, Hirai K et al (2002) Prospective trial of unilateral surgery for nonhereditary medullary thyroid carcinoma in patients without germline RET mutations. World J Surg 26:1023–1028 (RS)

    Article  PubMed  Google Scholar 

  5. Miyauchi A, Matsuzuka F, Hirai K et al (2000) Unilateral surgery supported by germline RET oncogene mutation analysis in patients with sporadic medullary thyroid carcinoma. World J Surg 24:1367–1372 (RS)

    Article  PubMed  CAS  Google Scholar 

  6. Ito Y, Miyauchi A, Yabuta T et al (2009) Alternative surgical strategies and favorable outcomes in patients with medullary thyroid carcinoma in Japan: experience of a single institution. World J Surg 33:58–66 (RS)

    Article  PubMed  Google Scholar 

  7. Grozinsky-Glasberg S, Benbassat CA, Tsvetov G et al (2007) Medullary thyroid cancer: a retrospective analysis of a cohort treated at a single tertiary care center between 1970 and 2005. Thyroid 17:549–556 (CS)

    Article  PubMed  Google Scholar 

  8. Greenblatt DY, Elson D, Mack E et al (2007) Initial lymph node dissection increases cure rates in patients with medullary thyroid cancer. Asian J Surg 30:108–112 (RS)

    Article  PubMed  Google Scholar 

  9. Dralle H, Scheumann GF, Proye C et al (1995) The value of lymph node dissection in hereditary medullary thyroid carcinoma: a retrospective, European, multicentre study. J Intern Med 238:357–361 (CS)

    Article  PubMed  CAS  Google Scholar 

  10. Scollo C, Baudin E, Travagli JP et al (2003) Rationale for central and bilateral lymph node dissection in sporadic and hereditary medullary thyroid cancer. J Clin Endocrinol Metab 88:2070–2075 (RS)

    Article  PubMed  CAS  Google Scholar 

  11. Machens A, Hauptmann S, Dralle H (2008) Prediction of lateral lymph node metastases in medullary thyroid cancer. Br J Cancer 95:586–591 (RS)

    CAS  Google Scholar 

  12. Machens A, Dralle H (2010) Biomarker-based risk stratification for previously untreated medullary thyroid carcinoma. J Clin Endocrinol Metab 95:2655–2663 (RS)

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Surgery, Noguchi Thyroid Clinic and Hospital Foundation, 6-33 Noguchinakamachi, Beppu, Oita, 874-0932, Japan

    Shinya Uchino

  2. Department of Breast and Endocrine Surgery, Toranomon Hospital, Tokyo, Japan

    Daishu Miura

  3. Department of Endocrine Surgery and Hygiene & Public Health II, Tokyo Women’s Medical University, Tokyo, Japan

    Takahiro Okamoto

Authors
  1. Shinya Uchino
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  2. Daishu Miura
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  3. Takahiro Okamoto
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Corresponding author

Correspondence to Shinya Uchino .

Editor information

Editors and Affiliations

  1. Ito Hospital, 4-3-6 Jinguumae, Shibuya-ku, Tokyo, 150-8308, Japan

    Hiroshi Takami

  2. , Department of Surgery, Kuma Hospital, 8-2-35 Shimoyamate-dori, Chuo-ku, Kobe, 650-0011, Japan

    Yasuhiro Ito

  3. Noguchi Thyroid Clinic and Hospital Foun, 6-33 Noguchinaka-machi, Beppu, 874-0932, Japan

    Hitoshi Noguchi

  4. , Department of Breast and Endocrine Surge, Kanagawa Cancer Center, 1-1-2 Nakao, Asahi-ku, Yokohama, 241-8515, Japan

    Akira Yoshida

  5. , Department of Endocrine Surgery, Tokyo Women's Medical University, 8-1 Kawada- cho, Shinjuku-ku, Tokyo, 162-8666, Japan

    Takahiro Okamoto

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© 2013 Springer Japan

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Uchino, S., Miura, D., Okamoto, T. (2013). CQ28. Do Total Thyroidectomy and Lymph Node Dissection for Sporadic and Hereditary Medullary Carcinoma Improve the Prognosis?. In: Takami, H., Ito, Y., Noguchi, H., Yoshida, A., Okamoto, T. (eds) Treatment of Thyroid Tumor. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54049-6_39

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  • DOI: https://doi.org/10.1007/978-4-431-54049-6_39

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  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-54048-9

  • Online ISBN: 978-4-431-54049-6

  • eBook Packages: MedicineMedicine (R0)

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