Abstract
Structural DNA nanotechnology enables us to design and fabricate shapes and patterns at nanoscale as a versatile platform for nanotechnology and bio-related computing. Since the introduction of crossover junctions, an endeavor to create nanostructures by DNA are now flourished as self-assemblies of various 2-D and 3-D shapes. Those achievements mainly owe to two factors: one is the geometry defined by crossover junctions, and the other is the introduction of design approach. The design approach itself is not dependent on any junction structure, however the lack of choice in junctions limits the appearance of resultant nanostructures. We found our interconnected single-duplex DNA junction extends the geometry of DNA nanostructures into a broader class of shapes and patterns. Here we propose an abstraction method that enables us to design variety of structures by those junctions with compatibility. Several demonstrations by this abstraction and possibilities of various new shapes and patterns based on the design approach are presented.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Seeman, N.C.: Nucleic acid junctions and lattices. J. Theor. Biol. 99(2), 237–247 (1982)
Fu, T.J., Seeman, N.C.: DNA double-crossover molecules. Biochemistry 32(13), 3211–3220 (1993)
Winfree, E., Liu, F., Wenzler, L.A., Seeman, N.C.: Design and self-assembly of two-dimensional DNA crystals. Nature 394(6693), 539–544 (1998)
Rothemund, P.W.K., Papadakis, N., Winfree, E.: Algorithmic self-assembly of DNA Sierpinski triangles. PLoS Biol. 2(12), e424 (2004)
Rothemund, P.W.K.: Folding DNA to create nanoscale shapes and patterns. Nature 440(7082), 297–302 (2006)
Douglas, S.M., Dietz, H., Liedl, T., Högberg, B., Graf, F., Shih, W.M.: Self-assembly of DNA into nanoscale three-dimensional shapes. Nature 459(7245), 414–418 (2009)
Yan, H., Park, S.H., Finkelstein, G., Reif, J.H., LaBean, T.H.: DNA-templated self-assembly of protein arrays and highly conductive nanowires. Science 301(5641), 1882–1884 (2003)
He, Y., Chen, Y., Liu, H., Ribbe, A.E., Mao, C.: Self-assembly of hexagonal DNA two-dimensional (2D) arrays. J. Am. Chem. Soc. 127(35), 12202–12203 (2005)
Hamada, S., Murata, S.: Substrate-assisted assembly of interconnected single duplex DNA nanostructures. Angew. Chem. Int. Ed. 48(37), 6820–6823 (2009)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Tokyo
About this paper
Cite this paper
Hamada, S., Murata, S. (2010). Extending the Geometrical Design of DNA Nanostructures. In: Peper, F., Umeo, H., Matsui, N., Isokawa, T. (eds) Natural Computing. Proceedings in Information and Communications Technology, vol 2. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53868-4_18
Download citation
DOI: https://doi.org/10.1007/978-4-431-53868-4_18
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-53867-7
Online ISBN: 978-4-431-53868-4
eBook Packages: Computer ScienceComputer Science (R0)