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Tiefe Hirnstimulation des Centrum-medianum-Nucleus-parafascicularis- Komplexes bei therapierefraktären Schmerzen

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Tiefe Hirnstimulation

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Zusammenfassung

Der thalamische CM-Pf-Komplex besteht aus den beiden Kernen Centrum medianum und Nucleus parafascicularis. Der französische Neurologe Jules Bernard Luys prägte Mitte des 19. Jahrhunderts die Bezeichnung „centre median“ [17], während die Bezeichnung Nucleus parafascicularis (Pf) auf die Terminologie von Cecile und Oskar Vogt zurückreicht [26]. Im klinischen Jargon häufig dem medialen Thalamus zugerechnet, gehören die beiden Kerne anatomisch gesehen jedoch zu den so genannten intralaminären Thalamuskernen, die innerhalb der Lamina medullaris interna thalami liegen und sich durch die Gemeinsamkeit striataler Efferenzen auszeichnen. Die Bezeichnung CM-Pf wird in den meisten Nomenklaturen für die thalamischen Kerne beim Versuchstier und auch in der speziesübergreifenden Nomenklatur nach Jones angewandt (siehe auch gesondertes Kapitel Anatomie und Nomenklatur der Basalganglien und des Thalamus in diesem Buch).

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Literatur

  1. Albe-Fessard D, Kruger L (1962) Duality of unit discharges from cat centrum medianum in response to natural and electrical stimulation. J Neurophysiol 25:3–20

    PubMed  CAS  Google Scholar 

  2. Andy OJ (1980) Parafascicular-center median nuclei stimulation for intractable pain and dyskinesia (painful-dyskinesia). Appl Neurophysiol 43:133–144

    PubMed  CAS  Google Scholar 

  3. Benabid AL, Henriksen SJ, McGinty JF, Bloom FE (1983) Thalamic nucleus ventro-postero-lateralis inhibits nucleus parafascicularis response to noxious stimuli through a non-opioid pathway. Brain Res 280:217–231

    Article  PubMed  CAS  Google Scholar 

  4. Bushnell MC, Duncan GH (1989) Sensory and affective aspects of pain perception: is medial thalamus restricted to emotional issues? Exp Brain Res 78:415–418

    Article  PubMed  CAS  Google Scholar 

  5. Davis KD, Lozano AM, Tasker RR, Dostrovsky JO (1998) Brain targets for pain control. Stereotact Funct Neurosurg 71:173–179

    Article  PubMed  CAS  Google Scholar 

  6. Fairman D (1966) Evaluation of results of stereotactic thalamotomy for the treatment of intractable pain. Confin Neurol 27:67–70

    Article  PubMed  CAS  Google Scholar 

  7. Gura EV, Garkavenko VV, Limansky Yu P (1991) Influences of central gray matter stimulation on thalamic neuron responses to high-and lowthreshold stimulation of trigeminal nerve structures. Neuroscience 41:681–693

    Article  PubMed  CAS  Google Scholar 

  8. Hariz MI, Bergenheim AT (1995) Thalamic stereotaxis for chronic pain: ablative lesion or stimulation? Stereotact Funct Neurosurg 64:47–55

    PubMed  CAS  Google Scholar 

  9. Hécaen H, Talairach J, David M, Dell MB (1949) Coagulations limitées du thalamus dans les algies du syndrome thalamique. Rev Neurol 81:917–931

    Google Scholar 

  10. Ishijima B, Yoshimasu N, Fukushima T, Hori T, Sekino H, Sano K (1975) Nociceptive neurons in the human thalamus. Confin Neurol 37:99–106

    Article  PubMed  CAS  Google Scholar 

  11. Krauss JK, Pohle T, Weigel R, Kalbarczyk A (2001) Somatosensory thalamic stimulation versus center median-parafascicular complex stimulation in 11 patients with neuropathic pain. Stereotact Funct Neurosurg 77:194

    Article  Google Scholar 

  12. Krauss JK, Pohle T, Weigel R, Burgunder JM (2002) Deep brain stimulation of the centre median-parafascicular complex in patients with movement disorders. J Neurol Neurosurg Psychiatry 72:546–548

    Article  PubMed  CAS  Google Scholar 

  13. Kunzle H (1977) Projections from the primary somatosensory cortex to basal ganglia and thalamus in the monkey. Exp Brain Res 30:481–492

    PubMed  CAS  Google Scholar 

  14. Kunzle H, Akert K (1977) Efferent connections of cortical, area 8 (frontal eye field) in Macaca fascicularis. A reinvestigation using the autoradiographic technique. J Comp Neurol 173:147–164

    Article  PubMed  CAS  Google Scholar 

  15. Laitinen LV (1977) Anterior pulvinotomy in the treatment of intractable pain. In: Sweet WH, Obrador S, Martin-Rodriguez JG, eds. Neurosurgi-cal treatment in Psychiatry, Pain and Epilepsy, Baltimore, London, Tokyo: University Park Press, 669–672

    Google Scholar 

  16. Laitinen LV (1988) Mesencephalotomy and thalamotomy for chronic pain. In: Lunsford LD (ed) Modern stereotactic neurosurgery. Martinus Nijhoff Publishing, Boston

    Google Scholar 

  17. Luys JB (1865) Recherches sur la Systeme nerveux cerebrospinal: sa structure, ses functions, et ses maladies. Bailliere, Paris

    Google Scholar 

  18. Mehler WR, Feferman ME, Nauta WJH (1960) Ascending axon degeneration following anterolateral cordotomy: An experimental study in the monkey. brain 83:718–750

    Article  PubMed  CAS  Google Scholar 

  19. Mundinger F, Salomao JF (1980) Deep brain stimulation in mesencephalic lemniscus medialis for chronic pain. Acta Neurochir (Suppl 30):245–258

    Article  Google Scholar 

  20. Niizuma H, Kwak R, Ikeda S, Ohyama H, Suzuki J, Saso S (1982) Follow-up results of centromedian thalamotomy for central pain. Appl Neurophysiol 45:324–325

    PubMed  CAS  Google Scholar 

  21. Niizuma H, Kwak R, Ohyama H, Ikeda S, Suzuki J, Saso S (1982) Centro-median thalamotomy for central pain following stroke — its effectiveness and limits. No Shinkei Geka 10:629–635

    PubMed  CAS  Google Scholar 

  22. Price DD (2000) Psychological and neural mechanisms of the affective dimension of pain. Science 288:1769–1772

    Article  PubMed  CAS  Google Scholar 

  23. Ray CD, Burton CV (1980) Deep brain stimulation for severe, chronic pain. Acta Neurochir Suppl 30:289–293

    Article  CAS  Google Scholar 

  24. Rinaldi PC, Young RF, Albe-Fessard D, Chodakiewitz J (1991) Spontaneous neuronal hyperactivity in the medial and intralaminar thalamic nuclei of patients with deafferentation pain. J Neurosurg 74:415–421

    Article  PubMed  CAS  Google Scholar 

  25. Thoden U, Doerr M, Dieckmann G, Krainick JU (1979) Medial thalamic permanent electrodes for pain control in man: an electrophysiological and clinical study. Electroencephalogr Clin Neurophysiol 47:582–591

    Article  PubMed  CAS  Google Scholar 

  26. Vogt C, Vogt O (1941) Thalamusstudien I-III. I. Zur Einführung. II. Homogenität und Grenzgestaltung der Grisea des Thalamus. III. Das Griseum centrale centrum medianum Luys. J Psychol Neurol 50:32–154

    Google Scholar 

  27. Watkins ES (1966) Stereotaxic thalamotomy for intractable pain. In: Meeting of the Harvey Cushing Society, April 19, St. Louis

    Google Scholar 

  28. Weigel R, Krauss JK (2004) Center median-parafascicular complex and pain control: review from a neurosurgical perspective. Stereotact Funct Neurosurg 82:115–126

    Article  PubMed  Google Scholar 

  29. White JC, Sweet WH (1969) Pain and the Neurosurgeon. A Forty Year Experience. Springfield, Illinois

    Google Scholar 

  30. Willis WD, Trevino DL, Coulter JD, Maunz RA (1974) Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb. J Neurophysiol 37:358–372

    PubMed  CAS  Google Scholar 

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Authors
  1. R. Weigel
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  2. J. K. Krauss
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Editor information

Editors and Affiliations

  1. Neurochirurgische Klinik, Universitätsklinikum Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany

    Joachim K. Krauss

  2. Neurologische Klinik, Universitätsklinikum Schleswig-Holstein - Campus Kiel, Schittenhelmstraße 10, 24105, Kiel, Germany

    Jens Volkmann

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© 2004 Springer-Verlag Berlin Heidelberg

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Weigel, R., Krauss, J.K. (2004). Tiefe Hirnstimulation des Centrum-medianum-Nucleus-parafascicularis- Komplexes bei therapierefraktären Schmerzen. In: Krauss, J.K., Volkmann, J. (eds) Tiefe Hirnstimulation. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-7985-1956-5_24

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  • DOI: https://doi.org/10.1007/978-3-7985-1956-5_24

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-62359-2

  • Online ISBN: 978-3-7985-1956-5

  • eBook Packages: Springer Book Archive

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