Ventricular function parameters and mass measured by MRI: acquisition, postprocessing, and reference values

  • J. T. Marcus
  • W. G. van Dockum
  • A. C. van Rossum


Accurate values of global left ventricular (LV) dimensions and mass are important in the diagnosis and prognosis of patients with heart disease. In patients who had a myocardial infarction, it has been proven that enlargement of the LV volume shortly after infarction implies a larger risk for LV remodeling and heart failure [27]. In patients suspected of suffering from ventricular hypertrophy, it is relevant to classify the LV mass accurately as either normal or increased. Also in many other cardiac diseases, such as valvular heart diseases and cardiomyopathies, the global LV dimensions, functional parameters, and mass need to be assessed.


Left Anterior Descend Right Coronary Artery Short Axis Slice Coronal View Global Left Ventricular 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Alfakih K, Plein S, Thiele H, Jones T, Ridgway JP, Sivananthan MU (2003) Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Res Imag 17:323–329CrossRefGoogle Scholar
  2. 2.
    Bloomgarden DC, Fayad ZA, Ferrari VA, Chin B, Sutton MG, Axel L (1997) Global cardiac function using fast breathhold MRI: validation of new acquisition and analysis techniques. Magn Res Med 37(5):683–692CrossRefGoogle Scholar
  3. 3.
    Bornstedt A, Nagel E, Schalla S, Schnackenburg B, Klein C, Fleck E (2001) Multi-slice dynamic imaging: complete functional cardiac MR examination within 15 s. J Magn Res Imag 14:300–305CrossRefGoogle Scholar
  4. 4.
    Carr JC, Simonetti O, Bundy J, Li D, Pereies S, Finn JP (2001) Cine MR angiography of the heart with segmented true fast imaging with steady-state precession. Radiology 219(3):828–834PubMedGoogle Scholar
  5. 5.
    Cerqueira MD, Weissman NJ, Dilsizian V et al (2002) Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. Circulation 105:539–542PubMedCrossRefGoogle Scholar
  6. 6.
    Cranney GB, Lotan CS, Dean L, Baxley W, Bouchard A, Pohost G (1990) Left ventricular volume measurement using cardiac axis nuclear magnetic resonance imaging: validation by calibrated ventricular angiography. Circulation 82: 154–163PubMedCrossRefGoogle Scholar
  7. 7.
    Doherty NE, Fujita N, Caputo GN, Higgins CB (1992) Measurement of right ventricular mass in normal and dilated cardiomyopathic ventricles using cine magnetic resonance imaging. Am J Cardiol 69:1223–1228PubMedCrossRefGoogle Scholar
  8. 8.
    Dubois D, Dubois EF (1916) A formula to estimate the approximate surface area if height and weight are known. Arch Int Med 17:863–871CrossRefGoogle Scholar
  9. 9.
    Götte MJW, Van Rossum AC, Marcus JT, Kuijer JPA, Axel L, Visser CA (1999) Recognition of infarct localization by specific changes in intramural myocardialmechanics. Am Heart J 138(6):1038–1045PubMedCrossRefGoogle Scholar
  10. 10.
    Katz J, Whang J, Boxt LM, Barst RJ (1993) Estimation of right ventricular mass in normal subjects and in patients with primary pulmonary hypertension by nuclear magnetic resonance imaging. J Am Coll Cardiol 21:1475–1481PubMedCrossRefGoogle Scholar
  11. 11.
    Koch JA, Poll LW, Godehart E, Modder U (2000) Determining left and right ventricular volume ejection fractions (VEF) with MRI at IT. Comparison of manual and semi-automated endocardium detection. Radiologe 40(2): 136–142PubMedCrossRefGoogle Scholar
  12. 12.
    Li W, Stern JS, Mai VM, Pierchala LN, Edelman RR, Prasad PV (2002) MR assessment of left ventricular function: quantitative comparison of fast imaging employing steady-state acquisition (FIESTA) with fast gradient echo cine technique. J Magn Res Imag 16:559–564CrossRefGoogle Scholar
  13. 13.
    Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham TP (1999) Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiov Magn Res 1:7–21CrossRefGoogle Scholar
  14. 14.
    Marcus JT, Götte MJW, Dewaal LK, Stam MR, Vander Geest RJ, Heethaar RM, Van Rossum AC (1999) The influence of through-plane motion on left ventricular volumes measured by Mag-netic resonance imaging: implications for image acquisition and analysis. J Cardiov Magn Res 1:1–6CrossRefGoogle Scholar
  15. 15.
    Marcus JT, DeWaal LK, Götte MJW, Van der Geest RJ, Heethaar RM, Van Rossum AC (1999) MRI-derived left ventricular function parameters and mass in healthy young adults: relation with gender and body size. Int J Cardiac Imaging 15:411–419CrossRefGoogle Scholar
  16. 16.
    Marcus JT, Götte MJW, Van Rossum AC, Kuijer JPA, Heethaar RM, Axel L, Visser CA (1997) Myocardial function in infarcted and remote regions early after infarction in man: assessment by magnetic resonance tagging and strain analysis. Magn Res Med 38:803–810CrossRefGoogle Scholar
  17. 17.
    Mogelvang J, Lindvig K, Sondergard L, Saunamaki K, Henndriksen O (1993) Reproducibility of cardiac volume measurements including left ventricular mass determined by MRI. Clin Physiol 13:587–597PubMedCrossRefGoogle Scholar
  18. 18.
    Nagel E, Schneider U, Schalla S, Ibrahim T, Schnackenburg B, Bornstedt A, Klein C, Lehmkuhl HB, Fleck E (2000) Magnetic resonance real-time imaging for the evaluation of left ventricular function. J Cardiov Magn Res 2(1):7–14CrossRefGoogle Scholar
  19. 19.
    Nidorf SM, Picard MH, Triulzi MO, Thomas JD, Newell J, King ME, Weyman AE (1992) New perspectives in the assessment of cardiac chamber dimensions during development and adulthood. J Am Coll Cardiol 19:983–988PubMedCrossRefGoogle Scholar
  20. 20.
    Pennell DJ (2002) Ventricular volume and mass by CMR. J Cardiov Magn Reson 4(4):507–513CrossRefGoogle Scholar
  21. 21.
    Rogers WJ, Shapiro EP, Weiss JL, Buchalter MB, Rademakers FE, Weisfeldt ML, Zerhouni EA (1991) Quantification of and correction for left ventricular systolic long axis shortening by magnetic resonance tissue tagging and slice isolation. Circulation 84:721–731PubMedCrossRefGoogle Scholar
  22. 22.
    Sandstede J, Lipke C, Beer M, Hofmann S, Pabst T, Kenn W, Neubauer S, Hahn D (2000) Age-and gender-specific differences in left and right ventricular cardiac function aand mass determined by cine magnetic resonance imaging. Eur Radiology 10(3):438–442CrossRefGoogle Scholar
  23. 23.
    Sechtem U, Pflugfelder PW, Gould RG, Cassidy MM, Higgins CB (1987) Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology 163: 697–702PubMedGoogle Scholar
  24. 23a.
    Thiele H, Paetsch I, Schnackenburg B, Bornstedt A, Grebe O, Wellnhofer E, Schuler G, Fleck E, Nagel E (2002) Improved accuracy of quantitative assessment of left ventricular volume and ejection fraction by geometric models with steady-state free precession. J Cardiovasc Magn Reson 4:327–339PubMedCrossRefGoogle Scholar
  25. 24.
    Underwood SR, Rees RSO, Savage PE, Klipstein RH, Firmin DN, Fox KM, Poole-Wilson PA, Longmore DB (1986) Assessment of regional left ventricular function by magnetic resonance. Br Heart J 56:334–340PubMedCrossRefGoogle Scholar
  26. 25.
    Van der Geest RJ, de Roos A, Van der Wall EE, Reiber JHC (1997) Quantitative analysis of cardiovascular MR images. Int J Card Imag 13: 247–258CrossRefGoogle Scholar
  27. 26.
    Van Rossum AC, Visser FC, Sprenger M, Van Eenige MJ, Valk J, Roos JP (1988) Evaluation of magnetic resonance imaging for the determination of left ventricular ejection fraction and comparison with angiography. Am J Cardiol 62:628–633PubMedCrossRefGoogle Scholar
  28. 27.
    White HD, Norris RM, Brown MA, Brandt PWT, Whitlock RML, Wild CJ (1987) Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 76:44–51PubMedCrossRefGoogle Scholar
  29. 28.
    Young AA, Cowan BR, Thrupp SF, Hedley Wj, Dell’Italia LJ (2000) Left ventricular mass and volume: fast calculation with guide point modeling on MR images. Radiology 216:597–602PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • J. T. Marcus
  • W. G. van Dockum
  • A. C. van Rossum

There are no affiliations available

Personalised recommendations