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“Noisy Oncology”: Some Caveats in using Gaussian Noise in Mathematical Models of Chemotherapy

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Aspects of Mathematical Modelling

Part of the book series: Mathematics and Biosciences in Interaction ((MBI))

Abstract

This article discusses some paradoxical results that arise when modelling uncertainties in models of anti-tumor chemotherapies using Gaussian noise. The effects of intrinsic and environmental perturbations and uncertainties on the dynamics of tumor growth and anti-tumor chemotherapy delivered via continuous infusion are considered.

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References

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Author information

Authors and Affiliations

  1. Division of Epidemiology and Biostatistics, European Institute of Oncology, Via Ripamonti, 435, Milano, Italy

    Alberto d’Onofrio

Authors
  1. Alberto d’Onofrio
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Editor information

Editors and Affiliations

  1. Dept. Mathematics, Universiti Brunei Darussalam, BE1410, Gadong, Brunei

    Roger J. Hosking

  2. Dipto. Matematica, Università di Torino, Via Carlo Alberto 10, 10123, Torino, Italy

    Ezio Venturino

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© 2008 Birkhäuser Verlag Basel/Switzerland

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d’Onofrio, A. (2008). “Noisy Oncology”: Some Caveats in using Gaussian Noise in Mathematical Models of Chemotherapy. In: Hosking, R.J., Venturino, E. (eds) Aspects of Mathematical Modelling. Mathematics and Biosciences in Interaction. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8591-0_12

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