Heavy metal poisoning: management of intoxication and antidotes

  • Daniel E. Rusyniak
  • Anna Arroyo
  • Jennifer Acciani
  • Blake Froberg
  • Louise Kao
  • Brent Furbee
Part of the Experientia Supplementum book series (EXS, volume 100)


Of the known elements, nearly 80% are either metals or metalloids. The highly reactive nature of most metals result in their forming complexes with other compounds such oxygen, sulfide and chloride. Although this reactivity is the primary means by which they are toxic, many metals, in trace amounts, are vital to normal physiological processes; examples include iron in oxygen transport, manganese and selenium in antioxidant defense and zinc in metabolism. With these essential metals toxicity occurs when concentrations are either too low or too high. For some metals there are no physiological concentrations that are beneficial; as such these metals only have the potential to cause toxicity. This chapter focuses on four of these: arsenic, mercury, lead and thallium.


Prussian Blue Lead Exposure Lead Poisoning Elemental Mercury Lead Toxicity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Verlag/Switzerland 2010

Authors and Affiliations

  • Daniel E. Rusyniak
    • 1
  • Anna Arroyo
    • 1
  • Jennifer Acciani
    • 1
  • Blake Froberg
    • 2
  • Louise Kao
    • 1
  • Brent Furbee
    • 1
  1. 1.Department of Emergency Medicine, Division of Medical ToxicologyIndiana University School of MedicineIndianapolisUSA
  2. 2.Department of Pediatrics, Division of Medical ToxicologyIndiana University School of MedicineIndianapolisUSA

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