Summary
We describe microelectrode recording and stimulation techniques to delineate the cellular boundaries and neural projections of stereotactic brain targets. These techniques have applications in the surgery for pain, movement disorders and in psychosurgery. Neuronal records from stereotactic operations including thalamotomy, pallidotomy, cingulotomy and anterior capsulotomy are discussed. These tools are used to distinguish gray matter from white matter, to obtain direct measures of cellular activity in the target, to identify the physiological properties and receptive fields of the subpopulation of neurons at the electrode tip and to avoid lesion making induced injury to adjacent structures. Microelectrode recording and stimulation techniques improve physiological localization and decrease the possibility of unwanted neurological complications with functional stereotactic procedures.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Benabid AL, Pollak P, Gervason C, et al (1991) Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet 337: 403–406
Delong M (1971) Activity of pallidal neurons during movement. J Neurophysiol 34: 414–427
Dostrovsky JO, Sher GD, Davis KD, Parrent AG, Hutchison WD (1993) Microinjections of lidocaine in the human thalamus: a useful tool in stereotactic surgery. Stereotact Funct Neurosurg 60: 168–174
Filion M, Tremblay L, Bedard PJ (1988) Abnormal influences of passive limb movement on the activity of globus pallidus neurons in parkinsonian monkeys. Brain Research 444: 165–176
Filion M, Tremblay L (1991) Abnormal spontaneous activity of globus pallidus neurons in monkeys with MPTP-induced parkinsonism. Brain Res 547: 142–151
Hassenbusch SJ, Pillay P, Barnett GH (1990) Radiofrequency Cingulotomy for intractable cancer pain using stereotaxis guided by magnetic resonance imaging. Neurosurgery 27: 220–223
Hutchison W, Lozano AM, Davis K, et al (1994) Differential neuronal activity in segments of globus pallidus in Parkinson’s disease patients. Neuro report 5: 1533–1537
Laitinen LV (1988) Psychosurgery today. Acta Neurochir (Wien) [Suppl] 44: 158–162
Laitinen LV, Bergenheim AT, Hariz MT (1992) Leksell’s posteroventral pallidotomy in the treatment of Parkinson’s disease. J Neurosurg 76: 53–61
Narabayashi H (1989) Stereotaxic VIM thalamotomy for treatment of tremor. Review Eur Neurol 29 [Suppl 1]: 29–32
Ohye C, Shibazaki T, Hirai T, et al (1989) Further physiological observations on the ventralis intermedius neurons in the human thalamus. J Neurophysiol 61: 488–500
Ohye C, Shibazaki T, Hirato M, et al (1990) Strategy of selective VIM thalamotomy guided by microrecording. Stereotact Funct Neurosurg 54–55: 186–191
Schaltenbrand G, Bailey P (1959) Einführung in die Stereotaktischen Operationen mit einem Atlas des menschlichen Gehirns, Vol 3. Thieme, Stuttgart
Siegfried J, Lippitz B (1994) Bilateral chronic electrostimulation of the ventroposterolateral pallidum: a new therapeutic approach for alleviating all parkinsonian symptoms. Neurosurgery 35: 1126–1130
Sterio D, Beric A, Dogali M, et al (1994) Neurophysiological properties of pallidal neurons in Parkinson’s disease. Ann Neurol 35: 586–591
Svennilison E, Torvik A, Lowe R, Leksell L (1960) Treatment of parkinsonism by stereotactic thermolesions in the pallidal region. Acta Psychiat Scand 35: 358–377
Tasker RR, Organ LW, Harylshyn PA (1982) The thalamus and midbrain of man: a physiological atlas using electrical stimulation. Thomas, Springfield, 111
Wichmann T, Delong MR (1993) Pathophysiology of parkinsonian motor abnormalities. Adv Neurol 60: 53–61
Yamashiro K, Tasker RR (1993) Stereotactic thalamotomy for dystonic patients. Stereotact Funct Neurosurg 60: 81–85
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag
About this paper
Cite this paper
Lozano, A.M., Hutchison, W.D., Dostrovsky, J.O. (1995). Microelectrode Monitoring of Cortical and Subcortical Structures During Stereotactic Surgery. In: Meyerson, B.A., Ostertag, C. (eds) Advances in Stereotactic and Functional Neurosurgery 11. Acta Neurochirurgica Supplementum, vol 64. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9419-5_7
Download citation
DOI: https://doi.org/10.1007/978-3-7091-9419-5_7
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-9421-8
Online ISBN: 978-3-7091-9419-5
eBook Packages: Springer Book Archive