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Radiosurgical Treatment of Gliomas of the Diencephalon

  • Conference paper
Advances in Radiosurgery

Part of the book series: Acta Neurochirurgica Supplementum ((NEUROCHIRURGICA,volume 62))

Summary

The results of Leksell Gamma Knife treatment of diencephalic gliomas are presented. Eight tumours in seven patients form the basis of this report. 7 patients, 4 males and 3 females. The age range was 7.5 to 33 years with a mean of 18 years. Mean follow-up was 21 ± 12 months. In 4 patients the tumour had been reduced in volume by an open internal decompression procedure. The location of the tumour will determine the risks of treatment. With anterior lesions there is risk of endocrinological and visual pathway damage. With a pineal region lesion there is a risk of diplopia.

In this series no tumour has increased in volume. Four have decreased and one has disappeared. Two patients suffered temporary diplopia. No visual disturbance has been observed to date. No hypothalamic disturbance has been observed yet.

These tumours are dangerous not so much because of their biological nature as because of their location. However, the biological nature of the tumours, with the close concordance between the radiological and actual extent make them appropriate targets for radiosurgery as a primary treatment. The present study gives preliminary support to this line of treatment.

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References

  1. Alexander E, Coffey RJ, Loeffler JS (1993) Radiosurgery of gliomas. In: Alexander E, Loeffler JS, Lunsford LD (eds) Stereotactic radiosurgery. McGraw Hill, New York, pp 207–219

    Google Scholar 

  2. Coffey RJ, Lunsford LD, Flickinger JC (1992) The role of radiosurgery in the treatment of malignant brain tumours. Neurosurg Clin N Am 3: 231–244

    PubMed  CAS  Google Scholar 

  3. Dempsey PK, Kondziolka D, Lunsford LD, Coffey RJ, Flickinger JC (1992) The role of stereotactic radiosurgery in the treatment of glial tumours. In: Lunsford LD (ed) Stereotactic radiosurgery update Elsevier, New York, pp 407–410

    Google Scholar 

  4. Ganz JC, Myrseth E, Thorsen F, Backlund E-O (1992) Acoustic schwannoma: early results of radiosurgical treatment. In: Tos M, Thomsen (eds) Acoustic neuroma. Kugler, Amsterdam, pp 301–304

    Google Scholar 

  5. Ganz JC, Backlund E-O, Thorsen FA (1993) The results of gamma knife surgery for meningiomas, related to size of tumour and dose. Stereotact Funct Neurosurg 61: 23–25

    Article  PubMed  Google Scholar 

  6. Inoue HK, Nakamura M, Ono N, Kohga H, Kakegawa T (1993) Long-term follow-up study of conventional irradiation for brain tumours in children: role of radiosurgery. Acta Neurochir (Wien) 122: 163

    Google Scholar 

  7. Inoue HK, Nakamura M, Ono N, Kawashima Y, Hirato M, Ohye C (1993) The long-term clinical effects of radiation therapy for primitive gliomas and medulloblastomas: a role for radiosurgery. Stereotact Funct Neurosurg 61: 51–58

    Article  PubMed  Google Scholar 

  8. Kilhstrom L, Karlsson B, Lindquist C (1992) Gamma knife surgery in brain metastases. In: Lunsford LD (ed) Stereotactic radiosurgery update. Elsevier, New York, pp 4429–434

    Google Scholar 

  9. Kilhstrom L, Karlsson B, Lindquist C (1993) Gamma knife surgery for cerebral metastases. Implications for survival based on 16 years experience. Stereotact Funct Neurosurg 61: 65–90

    Article  Google Scholar 

  10. Kondziolka D, Lunsford LD (1992) Radiosurgery of meningiomas. Neurosurg Clin N Am 3: 219–230

    PubMed  CAS  Google Scholar 

  11. Linskey ME, Lunsford LD, Flickinger JC, Kondziolka D (1992) Stereotactic radiosurgery for acoustic tumours. Neurosurg Clin N Am 3: 191–205

    PubMed  CAS  Google Scholar 

  12. Lunsford LD, Kondziolka D, Bissonette DJ, Maitz AH, Flickinger JC (1992) Stereotactic radiosurgery of brain vascular malformations. Neurosurg Clin N Am 3: 79–98

    PubMed  CAS  Google Scholar 

  13. Noren G, Arndt J, Hindmarsh T (1988) Stereotactic radiosurgical treatment of acoustic neurinomas. In: Lunsford LD (ed) Modern stereotactic neurosurgery. Martinus Nijhoff, Boston, pp 481–489

    Google Scholar 

  14. Noren G, Arndt J, Hindmarsh T (1983) Stereotactic radiosurgery in cases of acoustic neurinoma: further experiences. Neurosurgery 13: 12–22

    Article  PubMed  CAS  Google Scholar 

  15. Rubinstein L (1979) Tumours of the central nervous system. In: Firminger HI (ed) Atlas of tumour pathology. Second series, Fascicle 6. Castle House, Tunbridge Wells, pp 1–50

    Google Scholar 

  16. Scherer HJ (1938) Structural development in gliomas. Am J Cancer 34: 333–351

    Google Scholar 

  17. Steiner L, Lindquist C (1987) Radiosurgery in cerebral arteriovenous malformations. In: Tasker RR (ed) Neurosurgery: state of the art reviews. Stereotactic surgery. Hanley and Belfus, Philadelphia, pp 329–336

    Google Scholar 

  18. Steiner L, Lindquist C, Steiner M (1991) Meningiomas and gamma knife radiosurgery. In: Al-Mefty O (ed) Meningiomas. Raven, New York, pp 263–272

    Google Scholar 

  19. Sturm V, Kimmig B, Wowra B, Voges J, Schabbert S, Schlegel W, Pastyr O, Treuer H, Lorenz WJ (1992) Radiosurgery in malignant intracranial tumours. In: Steiner L, Lindquist C, Forster D, Backlund E-O (eds) Radiosurgery: baseline and trends. Raven, New York pp 155–160

    Google Scholar 

  20. Thorsen FA, Ganz JC (1993) Dose planning with the Leksell gamma knife: the effect on dose volume of more than one shot at the same target point. Stereotact Funct Neurosurg 61: 151–163

    Article  PubMed  Google Scholar 

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© 1994 Springer-Verlag

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Ganz, J.C., Smievoll, AI., Thorsen, F. (1994). Radiosurgical Treatment of Gliomas of the Diencephalon. In: Lindquist, C., Kondziolka, D., Loeffler, J.S. (eds) Advances in Radiosurgery. Acta Neurochirurgica Supplementum, vol 62. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9371-6_13

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  • DOI: https://doi.org/10.1007/978-3-7091-9371-6_13

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9373-0

  • Online ISBN: 978-3-7091-9371-6

  • eBook Packages: Springer Book Archive

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