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Wirkungen von Valproat auf die bioelektrische Aktivität einzelner Neurone

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Biologische Psychiatrie der Gegenwart

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Zusammenfassung

Die antiepileptischen Wirkungen von Valproat (VPA) treten verzögert ein und bleiben nach Absetzen verlängert bestehen [cf. 5]. In der vorliegenden Arbeit wird dargestellt, daß für dieses Wirkungsprofil ein intrazellulärer Wirkungsort in Kombination mit einer verzögerten Membrandurchlässigkeit verantwortlich sein kann.

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Literatur

  1. Altrup U, Gerlach G, Reith H, Said MN, Speckmann EJ (1992) Effects of valproate in a model nervous system (buccal ganglia of Helix pomatia). I. Antiepileptic actions. Epilepsia 33: 743–752

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Authors and Affiliations

  1. Institut für Experimentelle Epilepsieforschung, Hüfferstraße 68, D-48149, Münster, Bundesrepublik Deutschland

    Univ.-Prof. Dr. U. Altrup, A. Lehmenkühler, H. Reith, E.-J. Speckmann & J. Walden

Authors
  1. Univ.-Prof. Dr. U. Altrup
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  2. A. Lehmenkühler
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  3. H. Reith
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  4. E.-J. Speckmann
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  5. J. Walden
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Editor information

Editors and Affiliations

  1. Département Universitaire de Psychiatrie Adultes (DUPA), Route de Cery, CH-1008, Prilly-Lausanne, Switzerland

    Pierre Baumann

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© 1993 Springer-Verlag Wien

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Altrup, U., Lehmenkühler, A., Reith, H., Speckmann, EJ., Walden, J. (1993). Wirkungen von Valproat auf die bioelektrische Aktivität einzelner Neurone. In: Baumann, P. (eds) Biologische Psychiatrie der Gegenwart. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9263-4_70

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  • DOI: https://doi.org/10.1007/978-3-7091-9263-4_70

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-9264-1

  • Online ISBN: 978-3-7091-9263-4

  • eBook Packages: Springer Book Archive

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