Zusammenfassung
Interleukine sind eine Gruppe von löslichen glykosilierten Proteinen, die reaktiv auf Antigen- oder Mitogenstimulation von Monozyten, Makrophagen, T- und B-Lymphozyten gebildet werden. Auf solche Reize modifizieren sie die zelluläre Antwort als Entzündungsmediatoren (Chemotaxis, Fieber u. a.) und als interzelluläre Informationsmoleküle, die zur Zellproliferation und Zelldifferenzierung von immunkompetenten Zellen führen. Um ihrer Herkunft und ihrer Wirkung gerecht zu werden, bezeichnete man diese Faktoren als Interleukine (IL). Im Laufe der Zeit fand man jedoch, daß sowohl die Bildung als auch die Wirkung der Interleukine nicht auf Leukozyten beschränkt sind.
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© 1991 Springer-Verlag/Wien
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Reisinger, E.C., Brezinschek, H.P. (1991). Interleukine zur Therapie schwerer Infektionen. In: Deutsch, E., et al. Infektionen auf Intensivstationen. Intensivmedizinisches Seminar, vol 3. Springer, Vienna. https://doi.org/10.1007/978-3-7091-9130-9_19
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DOI: https://doi.org/10.1007/978-3-7091-9130-9_19
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