Summary
The visual cortex of the cat is characterized by marked modifiability of neuronal responsiveness by visual experience in infancy, and stereotyped pattern of functional architectures in adulthood. The question of how the plasticity of the infant visual cortex is compatible with the regular patterns of the adult visual cortex has been a central problem of the brain neuroscience. This question was answered by quantifying the plasticity in the visual cortical circuitry of the infant kittens as changes in synaptic transmission produced after conditioning stimulation of the visual pathway. The results indicate that the solution of this question is the heterogenous distribution of the synaptic plasticity in the infant visual cortex: the plasticity is not uniformly present in the visual cortical circuitry, but is limited only to a part of the circuitry (the cortico-cortical synapses in the supra-granular layers). Therefore, the visual function (photic responsiveness) may be learned during the postnatal life of the kittens by the supragranular cells with plastic synapses, while the other cortical cells with fewer plastic synapses put prenatally designed constraints on the learning, so that the learning yields the adult cortical circuitry with regular patterns of organization.
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References
Blakemore C, Cooper GF (1970) Development of the brain depends on the visual environment. Nature London 228: 477–478.
Blakemore C, Mitchell DE (1973) Environmental modification of the visual cortex and the neural basis of learning and memory. Nature (London) 241: 467–468.
Blakemore C, van Sluyters RC (1975) Innate and environmental factors in the development of the kitten’s visual cortex. J Physiol (London) 248: 663–716.
Blasdel GG, Mitchell DE, Muir DW, Pettigrew JD (1977) A physiological and behavioural study in cats of the effect of early visual experience with contours of a single orientation. J Physiol (London) 265: 615–636.
Buisseret P, Imbert M (1976) Visual cortical cells: Their developmental properties in normal and dark reared kittens. J Physiol (London) 255: 511–525.
Hebb DO (1949) The organization of behaviour. Wiley & Sons, New York.
Hirsch HVB, Spinelli DN (1970) Visual experience modifies distribution of horizontally and vertically oriented receptive fields in cats. Science 168: 869–871.
Hubel DH, Wiesel TN (1963) Receptive fields of cells in striate cortex of very young, visually inexperienced kittens. J Neurophysiol 26: 994–1002.
Hubel DH, Wiesel TN (1970) The period of susceptibility to the physiological effects of unilateral eye closure in kittens. J Physiol (London) 206: 419–436.
Komatsu Y, Fujii K, Nakajima S, Umetani K, Toyama K (1985) Electrophysiological and morphological correlates in the development of visual cortical circuity in infant kittens. Dev Brain Res 22: 305–309.
Komatsu Y, Toyama K, Maeda J, Sakaguchi H (1981) Long-term potentiation investigated in a slice preparation of striate cortex of young kittens. Neurosci Letters 26: 269–274.
Mitzdorf U, Singer W (1978) Prominent excitatory pathway in cat visual cortex (A 17 and A 18): a current source-density analysis of electrically evoked potentials. Exp Brain Res 33: 371–394.
Rauschecker JP, Singer W (1981) The effects of early visual experience on the cat’s visual cortex and their possible explanation by Hebb synapses. J Physiol (London) 310: 215–239.
Singer W, Freeman B, Rauschecker J (1981) Restriction of visual experience to a single orientation affects the organization of orientation columns in cat visual cortex: a study with deoxy-glucose. Exp Brain Res 41: 199–215.
Stryker MP, Sherk H, Leventhal AG, Hirsch HVB (1978) Physiological consequences for the cat’s visual cortex of effectively restricting early visual cortex with oriented contours. J Neurophysiol 41: 896–909.
Toyama K, Matsunami K, Ohno T, Tokashiki S (1974) An intracellular study of neuronal organization in the visual cortex. Exp Brain Res 21: 45–66.
Wiesel TN, Hubel DH (1963) Single cell responses in striate cortex of kittens deprived of vision in one eye. J Neurophysiol 26: 1003–1017.
Wiesel TN, Hubel DH (1965) Comparison of the effects of unilateral and bilateral eye closure on cortical unit responses in kittens. J Neurophysiol 28: 1029–1040.
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© 1987 Springer-Verlag/Wien
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Toyama, K., Komatsu, Y. (1987). Visual Cortical Plasticity in Infant Kittens. In: Sano, K., Ishii, S. (eds) Plasticity of the Central Nervous System. Acta Neurochirurgica Supplementum, vol 41. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8945-0_9
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DOI: https://doi.org/10.1007/978-3-7091-8945-0_9
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