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Analysis and Toxicological Safety Evaluation of Environmental Pollutants

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Book cover Nature, Aim and Methods of Microchemistry

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Abstract

Qualitative and quantitative changes in the exposure pattern of modern mankind to chemical, and the increasing awareness of new types of diseases caused by irreversible damages (mutagenesis, carcinogenesis, teratogenesis) have prompted a revision of safety testing strategies of drugs, and occupational and environmental chemicals. New elements of toxicological methodology are: pharmaco-kinetics, metabolism of xenobiotics, identification of toxic metabolites by examination of excretable and non-excretable reaction products with biomolecules, and short-term tests. Proper use of these elements in testing procedures decisively improves the prediction of toxic reactions in humans.

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References

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Authors and Affiliations

  1. Institute for Pharmacology and Toxicology, University of Würzburg, Versbacher Straße 9, D-8700, Würzburg, Federal Republic of Germany

    Dietrich Henschler

Authors
  1. Dietrich Henschler
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Editor information

H. Malissa M. Grasserbauer R. Belcher

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© 1981 Springer-Verlag/Wien

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Henschler, D. (1981). Analysis and Toxicological Safety Evaluation of Environmental Pollutants. In: Malissa, H., Grasserbauer, M., Belcher, R. (eds) Nature, Aim and Methods of Microchemistry. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8630-5_10

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  • DOI: https://doi.org/10.1007/978-3-7091-8630-5_10

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-81653-0

  • Online ISBN: 978-3-7091-8630-5

  • eBook Packages: Springer Book Archive

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