Abstract
Symptoms called akinesia in movement are analysed and classified into three groups. The first is that secondary to existence of marked rigidity of muscles and the second is that due to striatal dopamine deficieney, which simply be interpreted as “lack of movement”. The third is freezing or festination in quick repetitive movement especially in gait, Speech and handwriting, for which 1-Dopa therapy has no influence. Specific difficulty in the latter condition is found in the rhythm formation of repetitive movements when repetition is over 2 Hz, which the author named “hastening phenomenon converging into 5 Hz”.
However, the neural mechanism and pathology under the third group of akinesia is still not known. In most of the parkinsonian patients, it is considered that all three groups of akinesia are mixed together with variety of grade. Careful observations on the changes of clinical pictures through the course of 1-Dopa therapy and of stereotaxic surgery provided the analysis of so-called akinesia as described.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Barbeau, A.: Contributions of levodopa therapy to the neurophar- macology of akinesia. In: Parkinson’s Disease, Vol. 1 (. Siegfried, J., ed.), pp. 151–174. Bern: Huber. 1972.
Hornykiewicz, O.; Biochemical and pharmacological aspects of akinesia. In: Parkinson’s Disease, Vol. 1 (Siegfried, J., ed.), pp. 127 to 149. Bern: Huber. 1972.
Hughes, R. C., Polgar, J. G., Weightman, D., Walton, N.: Ldopa in parkinsonism and the influence of previous thalamotomy. Brit. med. J. 1, 7–13 (1974).
Imai, H., Narabayashi, H.: Akinesia (Jap.). Advanc. neurol. Sci. 18, 787–794 (1974).
Martin, Z.P..: The Basal Ganglia and Posture, pp. 7–19 and pp. 52 to 54.
Nakamura, R., Nagasaki, H., Narabayashi, H.: Arrhythmokinesia in parkinsonism. In: Advances in Parkinsonism (Birkmayer, W., et al., eds.), pp. 258–268. Basle: Roche. 1976.
Nakamura, R., Nagasaki, H., Narabayashi, H.: Disturbances of rhythm formation in patients with Parkinson’s disease: Pt. 1. Charac- teristics of tapping response to the periodic signals. Percept. Motor Skills 46, 63–75 (1978).
Narabayashi, H., Imai, H., Yokochi, M., Hirayama, K., Nakamura, R.: Cases of pure akinesia without rigidity and tremor and with no eifect by L-dopa therapy. In: Advances in Parkinsonism (Birkmayer, W., et al., eds.), pp. 335–342. Basle: Roche. 1976.
Narabayashi, H., Ohye, C.: Parkinsonian tremor and nucleus ventralis intermedius of the human thalamus. In: Progress in Clinical Neuro- physiology, Vol. 5 (Desmedt, J. E., ed.), pp. 165–172. Basel: Karger. 1978.
Ohye, C., Tsukahara, N., Narabayashi, H.: Rigidity and disturbance of reciprocal innervation. Confin. neurol. 26, 24–40 (1965).
Wertham, F.I.: A new sign of cerebellar disease. J. nerv. ment. Dis. 69, 486–493 (1929).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1980 Springer-Verlag
About this chapter
Cite this chapter
Narabayashi, H. (1980). Clinical Analysis of Akinesia. In: Carlsson, A., Jellinger, K., Riederer, P. (eds) Current Topics in Extrapyramidal Disorders. Journal of Neural Transmission, vol 16. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8582-7_13
Download citation
DOI: https://doi.org/10.1007/978-3-7091-8582-7_13
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-8584-1
Online ISBN: 978-3-7091-8582-7
eBook Packages: Springer Book Archive