Summary
The development of the clinical and EEG manifestations of intracortical alumina cream epileptogenic lesion is described in 14 split-brain cats. In 4 animals contralateral and/or ipsilateral, cortical and subcortical secondary epileptic foci were present. The results indicate that integrity of interhemispheric transfer through the corpus callosum and anterior and posterior commissures is not necessary for the transmission of epileptic activity to contralateral hemisphere. Partial epileptic seizures of Jacksonian type were observed in 6 cats. In 1 cat grand mal epileptic seizure developed. The possible mechanisms of secondary epileptic foci and generalized type of seizure are discussed.
This investigation was supported by a grant under Polish-American Agreement PL 480, NIMH, No. 05-276-2.
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© 1976 Springer-Verlag
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Majkowski, J., Pisarski, W., Bilińska-Nigot, B., Sobieszek, A., Karliński, A. (1976). Clinical and Electrophysiological Effects of Chronic Epileptic Lesion in Split-Brain Cats. In: Gillingham, F.J., Hitchcock, E.R., Nádvorník, P. (eds) Stereotactic Treatment of Epilepsy. Acta Neurochirurgica, vol 23. Springer, Vienna. https://doi.org/10.1007/978-3-7091-8444-8_11
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DOI: https://doi.org/10.1007/978-3-7091-8444-8_11
Publisher Name: Springer, Vienna
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