Summary
Much has been learned about the clinical symptomatology of Alzheimer’s disease (AD) and ontogenic reciprocal relationships in the past few decades. It is now possible to describe and verify inexorable symptomatic sequences and corresponding temporal relationships. It is also possible to identify more variable symptoms in AD. Ontogenic models can be useful in providing a clearer understanding of the nature of AD symptomatology in terms of both consistency and variability. These models can also be informative in explicating the management needs of AD patients and the treatment possibilities of AD symptoms as well as the etiology of variability in AD symptoms.
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Authors’ address: Dr. B. Reisberg, Alzheimer’s Disease Education and Resources Program, New York University Medical Center, New York, NY 10016, U.S.A.
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Reisberg, B., Franssen, E.H., Souren, L.E.M., Auer, S., Kenowsky, S. (1998). Progression of Alzheimer’s disease: variability and consistency: ontogenic models, their applicability and relevance. In: Gertz, HJ., Arendt, T. (eds) Alzheimer’s Disease — From Basic Research to Clinical Applications. Journal of Neural Transmission. Supplementa, vol 54. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7508-8_2
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