Zusammenfassung
Nachdem in den Dreißigerjahren die Konstitution der Sterole* und Gallensäuren und anschließend bald auch die der anderen Steroide (Sexualhormone, Nebennierenrinden-Hormone, Spirostanole, Cardenolide, Bufadienolide und Steranalkaloide) in den wesentlichen Grundzügen geklärt war, hat es nicht an Versuchen gefehlt, Einblick in den Weg der Biogenese dieser Stoffklasse zu gewinnen. Solange die Technik des biologischen Experiments mit markierten Verbindungen (Isotope) wenig entwickelt war, bestand keine Aussicht, die gemachten Hypothesen durch Versuche entscheidend zu kontrollieren. So gründeten sich diese vor allem auf Ähnlichkeiten gewisser Naturstoffe im chemischen Aufbau mit den Steroiden und auch auf das gemeinsame Vorkommen in biologischem Material. Nunmehr ist es möglich geworden, diese Vorstellungen mit den Ergebnissen der Tracer-Technik zu prüfen und auf ihren Wert hinsichtlich der Klärung des vorliegenden Problems zu untersuchen. Trotzdem sind wir heute noch weit davon entfernt, ein klares Bild von der Biogenese dieser Stoffklasse zu besitzen. Es dürfte nützlich sein, das gesamte Tatsachenmaterial einmal kritisch zu sichten, um einen Überblick über den derzeitigen Stand unseres Wissens zu geben.
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Von Tschesche, R. (1955). Neuere Vorstellungen auf dem Gebiete der Biosynthese der Steroide und verwandter Naturstoffe. In: Zechmeister, L. (eds) Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelŀes. Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progres dans la Chimie des Substances Organiques Naturelŀes, vol 12. Springer, Vienna. https://doi.org/10.1007/978-3-7091-7166-0_3
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