Stable Xenon CT/CBF Imaging: Laboratory and Clinical Experience

  • Howard Yonas
  • David Gur
  • Richard Latchaw
  • Sidney K. WolfsonJr.
Part of the Advances and Technical Standards in Neurosurgery book series (NEUROSURGERY, volume 15)


Since Winkler in 1977 determined that the radiodensity of xenon could be used for image enhancement during transmission computerized tomography44, a number of groups have explored the possibility of using stable xenon as a tracer of cerebral blood flow (CBF). In 1978, Kelcz and coworkers25 defined the CT enhancement characteristics of stable xenon at the same time that Drayer, et al.6 reported early experiments with the direct measurement of CBF. Since that time, work has continued in the search to determine the best route by which to characterize the time course of arterial and tisssue enhancement, as well as calculate CBF using this new technique.


Cerebral Blood Flow Brain Death Regional Cerebral Blood Flow Local Cerebral Blood Flow Xenon Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag/Wien 1987

Authors and Affiliations

  • Howard Yonas
    • 1
  • David Gur
    • 2
  • Richard Latchaw
    • 3
  • Sidney K. WolfsonJr.
    • 4
  1. 1.Department of Neurological SurgeryUniversity of PittsburghUSA
  2. 2.Department of Radiological ImagingUniversity of PittsburghUSA
  3. 3.Department of RadiologyPresbyterian University HospitalPittsburghUSA
  4. 4.Department of Neurological SurgeryMontefiore HospitalPittsburghUSA

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