Relationship between immune and behavioral measures in schizophrenia

  • D. P. van Kammen
  • C. G. McAllister
  • M. E. Kelley
Part of the Key Topics in Brain Research book series (KEYTOPICS)


Schizophrenia, which is a chronic but episodic disorder of unknown etiology, shares immunological features with organ specific autoimmune diseases such as multiple sclerosis (MS), rheumatoid arthritis and insulin-dependent diabetes mellitus. However, recent studies have raised the issue as to whether the reported immune disturbances in schizophrenia may be the result of a stress-induced dysregulation of CNS cytokine production, rather than a permanent immunological disorder, i.e., autoimmunity.


Negative Symptom Haloperidol Treatment Organ Specific Autoimmune Disease Episodic Disorder Negative Symp 
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Copyright information

© Springer-Verlag/Wien 1997

Authors and Affiliations

  • D. P. van Kammen
    • 1
    • 2
  • C. G. McAllister
    • 1
    • 2
  • M. E. Kelley
    • 1
  1. 1.Veterans Affairs Medical CenterUniversity of Pittsburgh, School of MedicinePittsburghUSA
  2. 2.Western Psychiatric Institute and ClinicUniversity of Pittsburgh, School of MedicinePittsburghUSA

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