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Hemifacial spasm: treatment with botulinum toxin (a report of 50 patients)

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Hemifacial Spasm

Summary

In this study the effectiveness of botulinum toxin injection in a group of 50 consecutive patients with hemifacial spasm was investigated. Two hundred and thirty injections were performed over a period of 46 months. Each patient received 2 to 12 injections (mean = 4.5). Mean delay of reinjection was 17.4 weeks. Mean duration of effective relief from spasms following all injections was 15 weeks. Ninety percent of patients improved more than 70%. Efficacy is maintained for up to 12 injections. Complications were noted in one-third of the injections: blurred vision (7.4%), excessive upper facial weakness (5.2%) or excessive lower facial weakness (5.6%), ptosis (4.3%), tearing (3.5%), and dry eye (1.7%). Any systemic effects were registered. Some questions related to botulinum toxin treatment are addressed.

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Author information

Authors and Affiliations

  1. EMG Laboratory, Botulinum Toxin Clinic, Hôpital Neurologique, Lyon, France

    Christophe Vial M.D. & A. Vighetto

Authors
  1. Christophe Vial M.D.
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  2. A. Vighetto
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Editor information

Editors and Affiliations

  1. Hôpital Neurologique, Lyon, France

    Marc Sindou

  2. Hôpital Henri Mondor, Creteil, France

    Yves Keravel

  3. Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, USA

    Aage R. Møller

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© 1997 Springer-Verlag/Wien

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Vial, C., Vighetto, A. (1997). Hemifacial spasm: treatment with botulinum toxin (a report of 50 patients). In: Sindou, M., Keravel, Y., Møller, A.R. (eds) Hemifacial Spasm. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6829-5_16

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  • DOI: https://doi.org/10.1007/978-3-7091-6829-5_16

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7416-6

  • Online ISBN: 978-3-7091-6829-5

  • eBook Packages: Springer Book Archive

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