Skip to main content

Neurophysiological bases of spasticity

  • Chapter
Neurosurgery for Spasticity

Abstract

Spasticity is an ill-defined term. Lance (1980) proposed an operational and relatively straightforward definition: “Spasticity is a motor disorder characterized by a velocity-dependent increase in tonic stretch reflexes (muscle tone) with exaggerated tendon jerks, resulting from hyperexcitability of the stretch reflex, as one component of the upper motor neuron syndrome.” This definition not only emphasizes the reflex nature of tone and spasticity, but also suggests that hypertonia is just one component of a more complex motor disorder that may be subsumed under the term “spastic syndrome”. In this contribution, I will argue that the reflex-notion of tone does not provide sufficient pathophysiological background for understanding the motor disorder of spasticity. Tone and posture is a prerequisite function for purposeful movements, often set in anticipation of goal-directed movements; what matters for the patient is how altered muscle tone is also expressed in voluntary movements. This chapter will first deal with these two aspects of tone, i.e. its reactive (reflexive) and its prospective (anticipatory) nature.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Benecke R, Conrad B, Meinck H-M (1984) Neue Erkenntisse zur Pathophysiologie der Spastizität. In: Conrad B, Benecke R, Bauer HI (Hrsg) Die klinische Wertung der Spastizität. Schattauer, Stuttgart New York, S 17–30

    Google Scholar 

  • Chen D-F, Bianchetti M, Wiesendanger M (1987) Involvement of noradrenergic systems in the modulation of cutaneous reflexes. In: Benecke C, Conrad B, Marsden CD (eds) Motor disturbances I. Academic Press, pp 179–186

    Google Scholar 

  • Conrad B, Benecke R, Meinck H-M (1985) Gait disturbances in paraspastic patients. In: Delwaide P, Young RR (eds) Clinical neurophysiology of spasticity. Elsevier, Amsterdam, pp 155–174

    Google Scholar 

  • Davidoff RA (1989) Actions of antispastic drugs. In: Emre M, Benecke R (eds) Spasticity: the current status of research and treatment. Parthenon, Carnforth, pp 115–124

    Google Scholar 

  • Delwaide PI (1985) Electrophysiological testing of spastic patients: its potential usefulness and limitations. In: Delwaide PI, Young RR (eds) Clinical neurophysiology in spasticity. Elsevier, Amsterdam, pp 185–203

    Google Scholar 

  • Evarts E (1984) Hierarchies and emergent features in motor control. In: Edelman GM, Gall WE, Cowan WM (eds) Dynamic aspects of neocortical function. Wiley, New York, pp 557–579

    Google Scholar 

  • Fulton IF (1951) Physiology of the nervous system, 3rd edn. Oxford University Press, New York, pp 157–193

    Google Scholar 

  • Granit R (1955) Receptors and sensory perception. Yale University Press, New Haven London

    Google Scholar 

  • Granit R (1979) Somme comments on ‘tone’. In: Granit R, Pompeiano O (eds) Reflex control of movements. Elsevier, Amsterdam (Prog Brain Res 50:17–29)

    Google Scholar 

  • Hagbarth KE, Wallin G, Löfstedt L (1973) Muscle spindle responses to stretch in normal and spastic subjects. Scand J Rehabil Med 5:156–159

    PubMed  CAS  Google Scholar 

  • Holstege JC, Kuypers HGIM (1987) Brainstem projections to spinal motoneurons: an update commentary. Neuroscience 23:809–821

    Article  PubMed  CAS  Google Scholar 

  • Hounsgaard J, Hultborn H, Kiehn O (1986) Transmitter-controlled properties of alpha-motoneurones causing long-lasting motor discharge to brief excitatory inputs. Prog Brain Res 64:39–49

    Article  PubMed  CAS  Google Scholar 

  • Lance IW (1980) Symposium synopsis. In: Feldman RG, Young RR, Koella WP (eds) Spasticity: disordered motor control. Year Book Medical Publ, Chicago London, pp 485–500

    Google Scholar 

  • Massion J (1984) Postural changes accompanying voluntary movements. Normal and pathological aspects. Hum Neurobiol 2:261–267

    PubMed  CAS  Google Scholar 

  • McCouch GP, Austin GM, Liu CN, Liu CY (1958) Sprouting as a cause of spasticity. J Neurophysiol 21:205–216

    PubMed  CAS  Google Scholar 

  • Nashner LM, McCollum G (1985) The organization of human postural movements: a formal basis and experimental synthesis. Behav Brain Sci 8:135–172

    Article  Google Scholar 

  • Penn RD (1989) Intrathecal medications for spasticity. In: Emre M, Benecke R (eds) Spasticity: the current status of research and treatment. Parthenon, Carnforth, pp 125–129

    Google Scholar 

  • Pierrot-Deseilligny E, Mazieres L (1985) Spinal mechanisms underlying spasticity. In: Delwaide PI, Young RR (eds) Clinical neurophysiology in spasticity. Elsevier, Amsterdam, pp 63–76

    Google Scholar 

  • Rhines R, Magoun HW (1946) Brain stem facilitation and cortical motor response. J Neurophysiol 9:219–229

    PubMed  CAS  Google Scholar 

  • Rushworth G, Lishman WA, Hughes JT, Oppenheimer DR (1961) Intense rigidity of the arms due to isolation of motoneurones by a spinal tumor. J Neurol Neurosurg Psychiatry 24:132–142

    Article  PubMed  CAS  Google Scholar 

  • Sherrington C (1947) The integrative action of the nervous system, 2nd edn. Yale University Press, New Haven

    Google Scholar 

  • Wiesendanger M (1967) Morphological, electro physiological and pathological aspects of interneurones. Electroencephalogr Clin Neurophysiol [Suppl] 25:45–58

    Google Scholar 

  • Wiesendanger M (1981) The pyramidal tract. Its structure and function. In: Towe A, Luschei E (eds) Handbook of behavioral neurobiology, vol 5. Plenum, New York, pp 401–491

    Google Scholar 

  • Wiesendanger M (1984) Pyramidal tract function and the clinical ‘pyramidal syndrome’. Hum Neurobiol 2:227–234

    PubMed  CAS  Google Scholar 

  • Wiesendanger M (1985) Is there an animal model of spasticity? In: Delwaide PJ, Young RR (eds) Clinical neurophysiology of spasticity. Elsevier, Amsterdam, pp 1–12

    Google Scholar 

  • Wiesendanger M (1989) Neurobiology of spasticity. In: Emre R, Benecke R (eds) Spasticity-the current states of research and treatment. Parthenon, Carnforth, pp 45–61

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Wien

About this chapter

Cite this chapter

Wiesendanger, M. (1991). Neurophysiological bases of spasticity. In: Sindou, M.P., Abbott, I.R., Keravel, Y. (eds) Neurosurgery for Spasticity. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6708-3_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-6708-3_2

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7388-6

  • Online ISBN: 978-3-7091-6708-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics