Interactions Between Agrobacterium tumefaciens and Its Host Plant Cells

  • Stephen C. Winans
Part of the Plant Gene Research book series (GENE)


Agrobacterium tumefaciens is the causative agent of the crown gall disease of dicotyledonous plants (Smith and Townsend, 1907; reviewed in Braun, 1982). The finding 13 years ago that the bacterium can transfer a discrete segment of tumorigenic DNA (T-DNA) to the genome of the plant host (Chilton et aI., 1977, 1980; Willmitzer, 1980) attracted the interest ofa large number of laboratories around the world. This was largely due to the possibility of exploiting this unprecedented interkingdom DNA transfer to create transgenic plants. There have been at least two consequences of this research. The first is that Agrobacterium has indeed been used to create transgenic plants of several dozen species containing genes of scientific or commercial importance. The second consequence, perhaps somewhat accidental, is that Agrobacterium now provides the best available model for studying the molecular interactions between plants and their bacterial pathogens.


Hairy Root Agrobacterium Tumefaciens Crown Gall Bottom Strand Crown Gall Disease 
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Copyright information

© Springer-Verlag Wien 1992

Authors and Affiliations

  • Stephen C. Winans
    • 1
  1. 1.Section of MicrobiologyCornell UniversityIthacaUSA

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