Abstract
When you consider pulmonary hemodynamics in obstructive sleep apnea, obviously the question is: what is the link between the occurrence of apneas during sleep and the development of what was called the “Pickwickian syndrome”? - that is, a picture of a fat, sleepy patient who has cardiorespiratory failure. This was the question behind the first studies. The early studies which have been performed in this field were reported in a very early paper published in the 1972 report of the Rimini Meeting; Coccagna and coworkers showed that the pulmonary arterial pressure increased during sleep as compared to baseline pulmonary arterial pressure during the awake state. This increase appeared during the obstructive apnea episodes, with a further increase on breathing resumption. They also stressed the very marked oscillations during the obstructive episodes related to the ineffective respiratory episodes.
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References
Bradley T.O., Rutherford R., Grossman R.F., Lue F., Zamel N., Moldofsky H., Phillipson E.A.: Role of daytime hypoxemia in the pathogenesis of right heart failure in the obstructive sleep apnea syndrome. Am Rev Respir Dis (1985) 131: 835–839.
Coccagna G., Mantovani M., Brignani F., Parchi C., Lugaresi E.: Continuous recording of the pulmonary and systemic arterial pressure during sleep in syndromes of hypersomnia with periodic breathing. Bull Physiopathol Respir (1972) 8: 1159–1172.
Guyton A.C., Lindsey A.W., Abernathy B., Richardson T.: Venous return at various right atrial pressures, and the normal venous return curve. Am J Physiol (1957) 189: 609–615.
Krieger J., Follenius M., Sforza E., Brandenberger G., Peter J.D.: Effects of treatment with nasal continuous positive airway pressure on atrial natriuretic peptide and arginine vasopressin release during sleep in obstructive sleep apnea. Clin Sci (1991) 80: 443–449.
Krieger J., Laks L., Wilcox I., Grunstein R.R., Costas L.J.V., McDougall J.G., Sullivan C.E.: Atrial natriuretic peptide release during sleep in patients with obstructive sleep apnoea before and during treatment with nasal continuous positive airway pressure. Clin Sci (1989) 77: 407–411.
Krieger J., Sforza E., Apprill M., Lampert E., Weitzenblum E., Ratomaharo J.: Pulmonary hypertension, hypoxemia, and hypercapnia in obstructive sleep apnea patients Chest (1989) 96: 729–737.
Krieger J., Weitzenblum E: Pulmonary hemodynamics in the obstructive sleep apnea syndrome. In: Sleep and health risk. Eds, Peter J.H., Penzel T., Podszus T., Von Wichert; Springer, Berlin, 1991, pp 356–363.
Krieger J.: Mechanisms of daytime pulmonary hypertension and altered renal function in obstructive sleep apnea. In: Obstructive sleep apnea syndrome. Clinical Research and Treatment. Eds, Guilleminault C., Partinen M. Raven Press, New York, 1990, pp 71–80.
Londsdorfer J., Meunier-Carus J., Lampert-Benignus E., et al: Aspects hemodynamiques et respiratoires du syndrome pickwickien. Bull Physiopath Resp (1972) 8: 1181–1192.
Marrone O., Bellia U., Ferrara G., Milone F., Romano L, Salvaggio A., Stallone A., Bonsignore G.: Transmural pressure measurements: importance in the assessment of pulmonary hypertension in obstructive sleep apneas. Chest (1989) 95: 338–343.
Marrone O, Ferrara G., Macaluso C., Milone F., Cibella F., Bellia V., Bonsignore G.: Hemodynamics in obstructive sleep apnea syndrome patients treated by continuous positive airway pressure. In: Sleep related disorders and internal diseases. Eds, Peter J.H., Podszus T., Wichert P. von. Springer, Berlin Heidelberg New York, 1987, pp 375–379.
Schroeder J.S., Motta J., Guilleminault C.: Hemodynamic studies in sleep apnea. In: Sleep apnea syndromes. Eds, Guilleminault C, Dement W.C., Alan R. Liss, New York, 1978, pp 177–196.
Weitzenblum E., Krieger J., Apprill M., Vallee E., Erhart M., Ratamaharo J., Oswald M., Kurtz D.: Daytime pulmonary hypertension in patients with obstructive sleep apnea syndrome. Am Rev Respir Dis (1988) 138: 345–349.
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© 1992 Springer-Verlag Wien
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Krieger, J. (1992). Pulmonary Hemodynamics in Sleep Apnea. In: Zwick, H. (eds) Sleep Related Breathing Disorders. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6675-8_2
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DOI: https://doi.org/10.1007/978-3-7091-6675-8_2
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-82376-7
Online ISBN: 978-3-7091-6675-8
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