Predictors of outcome in schizophrenia: the concept of time
The ability to predict the treatment response of patients with schizophrenia has been the goal of an extensive number of studies (reviewed in Lieberman and Kane 1986, Lieberman and Sobel 1993, Lieberman and Koreen 1993, Lieberman et al. 1994). Measures that have been examined as potential predictors of treatment outcome can be classified into several categories. These include historical, constitutional, environmental, phenomenologic and biologic variables. The ability of these measures to be predictive of treatment outcome is dependent on in what phase of the illness they are being assessed and when in the course of illness outcome is being assessed. In addition, there are a number of factors that can influence the expression and ability to identify measures that might be predictive of treatment outcome (Table 1).
KeywordsGood Treatment Outcome Neurologic Soft Sign Island Jewish Medical Primary Negative Sign Antipsychotic Drug Dose
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