Summary
Brain tissue PO2 in severely head injured patients was monitored in parallel with two different PO2-microsensors (Licox and Paratrend). Three different locations of sensor placement were chosen: (1) both catheters into non lesioned tissue (n = 3), (2) both catheters into contusioned tissue (n = 2), and (3) one catheter (Licox) into pericontusional versus one catheter (Paratrend) into non lesioned brain tissue (n = 2). Mean duration of PtiO2-monitoring with both microsensors in parallel was 68.1 hours. Brain tissue PO2 varied when measured in lesioned and nonlesioned tissue.
In non lesioned tissue both catheters closely correlated (Δ Licox/Paratrend: mean PtiO2 < 5 mm Hg) after 20 hours post insertion. In pericontusional tissue PtiO2 was reduced relative to non lesioned tissue (Δ lesioned/non lesioned: mean PtiO2: 10.3mmHg). In contusioned brain tissue PtiO2 was always below the “hypoxic threshold” of 10mmHg, independent of the type of micorsensor used. During a critical reduction in cerebral perfusion pressure (<60mmHg), PtiO2 decreased measured with both microsensors. Elevation of inspired oxygen fraction, normally followed by a rapid increase in tissue PO2, only increased PtiO2 when measured in pericontusional and nonlesioned brain. To recognize critical episodes of hypoxia or ischemia, PtiO2-monitoring of cerebral oxygenation is recommended in nonlesioned brain tissue.
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© 1998 Springer-Verlag Wien
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Sarrafzadeh, A.S., Kiening, K.L., Bardt, T.F., Schneider, GH., Unterberg, A.W., Lanksch, W.R. (1998). Cerebral Oxygenation in Contusioned vs. Nonlesioned Brain Tissue: Moniting of PtiO2 with Licox and Paratrend. In: Marmarou, A., et al. Intracranial Pressure and Neuromonitoring in Brain Injury. Acta Neurochirurgica Supplements, vol 71. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6475-4_54
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DOI: https://doi.org/10.1007/978-3-7091-6475-4_54
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