Summary
The aim of the study was to find out whether there is a correlation between the tissue-pO2 (ti-pO2) measurement and the lactate-oxygen index (mLOI). Both methods are to be considered as methods to detect brain ischemia. We studied 7 patients after severe head injury (GCS < 8) with a jugular bulb catheter and a tissue pO2 probe. Possible ischemia was defined with ti-pO2 below 10 mmHg and mLOI above 0.08. 67 pairs of ti-pO2 and corresponding mLOI were found. In 5 cases out of the 7 cases with a ti-pO2 below 10 we found a pathological mLOI above 0.08. In 11 cases with pathological mLOI values, however, we found only 6 cases of decreased ti-pO2. The absolute values did not correlate. The sensitivity to predict normal values is above 85% with both methods. The specifity to predict ischemia is low (<72%). The reason is the fact, that ti-pO2 is a local method in contrast to the mLOI values. In cases of diffuse brain injury without major contusions there should be a correlation between ti-pO2 and the mLOI.
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References
Chesnut RM, Marshall LF, Klauber MR, Blunt BA, Baldwin N, Eisenberg HM, Jane JA, Marmarou A, Foulkes MA (1993) The role of secondary brain injury in determining outcome from severe head injury. J Trauma 34(2): 216–222
Cruz J, Hoffstadt OJ, Jaggi JI (1994) Cerebral blood flow, vascular resistance, and oxygen metabolism in acute brain trauma: redefining the role of cerebral perfusion pressure? Crit Care Med 22: 1465–1470
Maas AIR, Fleckenstein W, de Jong DA, van Santbrink H (1993) Monitoring cerebral oxygenation: Experimental studies and preliminary clinical results of continuous monitoring of cerebrospinal fluid and brain tissue oxygen tension. Acta Neurochir (Wien) [Suppl] 59: 50–57
Marshall LF, Marshall SB, Klauber MR (1991) A new classification of head injury based on computerized tomography. J Neurosurg 75 [Suppl]: S14–S20
Robertson CS, Contant CF, Gokaslan ZL, Narayan RK, Grossman RG (1992) Cerebral blood flow, arteriovenous oxygen difference and outcome in head injured patients. J Neurol Neurosurg Psychiatry 55: 594–603
Robertson CS (1993) Desaturation episodes after severe head injury: Influence on Outcome. Acta Neurochir (Wien) [Suppl] 59: 98–101
van Santbrink H, Maas AIR, Avezaat CJJ (1996) Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurgery 38: 21–31
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© 1998 Springer-Verlag Wien
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Holzschuh, M., Metz, C., Woertgen, C., Rothörl, R.D., Brawanski, A. (1998). Brain Ischemia Detected by Tissue-PO2 Measurement and the Lactate-Oxygen Index in Head Injury. In: Marmarou, A., et al. Intracranial Pressure and Neuromonitoring in Brain Injury. Acta Neurochirurgica Supplements, vol 71. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6475-4_49
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DOI: https://doi.org/10.1007/978-3-7091-6475-4_49
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