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Langzeitbehandlung schizophrener Erkrankungen: Konzept, Methoden, Strategien

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Schizophrenie — Moderne Konzepte zu Diagnostik, Pathogenese und Therapie

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Zusammenfassung

Mit der Bezeichnung „Gruppe der Schizophrenien“ hat Bleuler (1911) auf die Heterogenität schizophrener Krankheitsbilder und Verläufe aufmerksam gemacht — in Abgrenzung gegenüber Kraepelin (1919), für den ein defektuöser Verlauf der „Dementia praecox“ gegeben war. Verlaufsergebnisse jahrzehntelanger Katamnesen zeigen (Bleuler et al. 1976, McGlashan 1991), daß der Verlaufsausgang schizophrener Psychosen zwar schlechter als der affektiver Psychosen, aber durchaus variabel ist. Dabei nehmen schizoaffektive Psychosen eine gewisse Mittelstellung ein. Diese Variabilität, die sowohl auf eine ätiopathogenetische Heterogenität i.S. einer multifaktoriellen Krankheitsgenese als auch auf eine Verlaufsplastizität zurückgeführt wird, eröffnet heute gut begründete therapeutische Möglichkeiten.

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  1. Rheinische Kliniken Düsseldorf, Kliniken der Heinrich-Heine-Universität, Bergische Landstraße 2, D-40629, Düsseldorf, Bundesrepublik Deutschland

    Prof. Dr. med. W. Gaebel

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  1. Prof. Dr. med. W. Gaebel
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  1. Psychiatrische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Nußbaumstraße 7, D-80336, München, Bundesrepublik Deutschland

    Hans-Jürgen Möller  & Norbert Müller  & 

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Gaebel, W. (1998). Langzeitbehandlung schizophrener Erkrankungen: Konzept, Methoden, Strategien. In: Möller, HJ., Müller, N. (eds) Schizophrenie — Moderne Konzepte zu Diagnostik, Pathogenese und Therapie. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6471-6_25

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  • DOI: https://doi.org/10.1007/978-3-7091-6471-6_25

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