Abstract
Microdialysis (MD) is a new technique which allows the continuous acquisition of samples from a limited area of the brain with good temporal resolution. This method enables the retrieval of critical biochemical substances from the extracellular fluid (ECF) of the brain, thus representing a valid tool for studying the mechanisms of cerebral secondary ischemia in humans [10, 11, 12]. One of the most common causes of unfavorable outcome following subarachnoid aneurysmal hemorrhage (SAH) is cerebral vasospasm-induced delayed ischemia, often leading to reversible or perma- nent neurological deficits as a consequence of neuronal damage or death [6, 10]. Vasospasm is generally a focal rather than diffuse phenomenon and development is not always detected early by TCD evaluation nor by routine neuroradiological exams; therefore, a technique such as MD may be important for direct neurochemical monitoring.
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© 2001 Springer-Verlag
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De Micheli, E. et al. (2001). Monitoring Subtle Neurometabolic Changes in Subarachnoid Hemorrhage Patients Using Microdialysis: A Study on 16 Cases. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_32
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_32
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