Abstract
There have been controversies regarding the influence of aging on the degree of vasospasm after subarachnoid hemorrhage. Most of the previous reports are studies based upon clinical data and there have not been detailed experimental studies. Contractile responses of cerebral arteries to vasoconstricting agents have been demonstrated to be increased with age, athelosclerosis and hypertension [4]. The cause of vasospasm is considered multifactorial, thus aging might influence the degree of vasospasm. Issues related to intraarterial infusion of papaverine for the treatment of vasospasm have often been discussed 3]. However, vasodilating responses induced by papaverine in young and in old arteries have not been compared. The present study was conducted to clarify age-related differences in vasospasm and the efficacy of papaverine.
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© 2001 Springer-Verlag
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Date, I. et al. (2001). Comparison of Cerebral Vasospasm Between Young and Old Animals: Preliminary Report. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_24
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_24
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-83650-7
Online ISBN: 978-3-7091-6232-3
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