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Endothelin: The “Prime Suspect” in Cerebral Vasospasm

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Cerebral Vasospasm

Part of the book series: Acta Neurochirurgica Supplements ((NEUROCHIRURGICA,volume 77))

Abstract

Endothelin (ET)-l has demonstrated a wide variety of effects throughout the body. Studies have shown effects on bronchial constriction, on the kidneys, even as a potential neurotransmitter [20, 27, 40, 44]. Its effects on the vasculature have been widely studied [8, 32, 45]. Specifically, ET-1 has been studied with respect to its role in the development of subarachnoid hemorrhage (SAH)-induced vasospasm. Following is a summary of ET-1 and its role in SAH-induced vasospasm.

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Authors and Affiliations

  1. Department of Neurosurgery, The Neuroscience Institute, Mayfield Clinic and Spine Institute, University of Cincinnati College of Medicine, Cincinnati, OH, USA

    M. Zuccarello M.D.

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  1. M. Zuccarello M.D.
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Editors and Affiliations

  1. Inselspital, Neurochirurgische Univ.-Klinik, Bern, Switzerland

    R. W. Seiler

  2. Klinikum Großhadern, Neurochirurgische Univ.-Klinik, München, Germany

    H.-J. Steiger

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© 2001 Springer-Verlag

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Zuccarello, M. (2001). Endothelin: The “Prime Suspect” in Cerebral Vasospasm. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_14

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  • DOI: https://doi.org/10.1007/978-3-7091-6232-3_14

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-83650-7

  • Online ISBN: 978-3-7091-6232-3

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