Abstract
Elongated, dumbbell-shaped mitochondria, containing longitudinal stacks of lamellae, have been described in the liver of rats subjected to certain toxic agents, such as ammonium carbonaie or dinitrophenol; their occurrence and particular morphology have been considered to be the expression of degenerative processes, and the intramitochondrial lamellae likened to myelin figures [1, 2]. Dumbbell-shaped or elongated forms of mitochondria, with apparently concentric longitudinal cristae have been observed in rats following administration of thyroxine in excess [3]. Lehninger has pointed out that the latter extended or dumbbell-shaped configurations may be related to mitochondrial growth and division [4].
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References
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Claude, A. (1967). Mitochondrial Cristae during Liver Regeneration. In: Bolis, L., Capraro, V., Porter, K.R., Robertson, J.D. (eds) Symposium on Biophysics and Physiology of Biological Transport. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5577-6_55
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DOI: https://doi.org/10.1007/978-3-7091-5577-6_55
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