Abstract
The hypothermic state may be divided into 4 stages: clinical, surgical, deep or profound, and frozen or supercooled. The clinical stage extends from 35° to 32° C, surgical from 32° to 25° C, deep or profound from 25° to 0° C, and the frozen or supercooled from 0° to—8° C. Each stage has characteristic physiological activities, and each, within prescribed limits, is compatible with survival and restoration of complete integrity upon rewarming. It is clear that the low temperature slows the rate of cellular processes and modifies the action of metabolities and other substances. This is not necessarily harmful, as long as anoxia and chemical imbalance do not develop.
This study was supported by Kesearch Grant B-2469 from the National Institute of Neurological Diseases and Blindness, U. S. P. H. S.
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© 1964 Springer-Verlag/Wien
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Rosomoff, H.L. (1964). Pathophysiology of the Central Nervous System During Hypothermia. In: Maspes, P.E., Hughes, B. (eds) Hypothermia in Neurosurgery. Acta Neurochirurgica, vol 13. Springer, Vienna. https://doi.org/10.1007/978-3-7091-5474-8_2
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DOI: https://doi.org/10.1007/978-3-7091-5474-8_2
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