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Studies on the Control of Pineal Indole Synthesis: Cyclic Nucleotides, Adenylate Cyclase and Phosphodiesterase

  • Conference paper
The Pineal Gland

Part of the book series: Journal of Neural Transmission ((NEURAL SUPPL,volume 13))

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Summary

An overview of the biochemical events that occur when postsynaptic pineal beta-adrenergic receptors are stimulated is presented. Emphasis is placed on the importance of the adenylate cyclase system for the induction of N-acetyltransferase (NAT). Super- and subsensitive responses of NAT to receptor agonists are related to cAMP concentration, adenylate cyclase and Phosphodiesterase activities and receptor binding sites.

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Authors and Affiliations

  1. Neuropsychopharmacology Research Unit, Department of Psychiatry, New York University Medical Center, New York City, New York, USA

    M. A. Oleshansky

  2. Laboratory of Preclinical Pharmacology, National Institute of Mental Health, St. Elizabeths Hospital, Washington, D.C., 20032, USA

    Dr. N. H. Neff

Authors
  1. M. A. Oleshansky
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  2. Dr. N. H. Neff
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Faculty of Medicine, Hadassah Medical Center, Jerusalem, Israel

    Isaac Nir

  2. Department of Anatomy, The University of Texas, San Antonio, Texas, USA

    Russel J. Reiter

  3. Laboratory of Neuroendocrine Regulation, Department of Nutrition and Food Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Richard J. Wurtman

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© 1978 Springer-Verlag Wien

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Oleshansky, M.A., Neff, N.H. (1978). Studies on the Control of Pineal Indole Synthesis: Cyclic Nucleotides, Adenylate Cyclase and Phosphodiesterase. In: Nir, I., Reiter, R.J., Wurtman, R.J. (eds) The Pineal Gland. Journal of Neural Transmission, vol 13. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4427-5_8

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  • DOI: https://doi.org/10.1007/978-3-7091-4427-5_8

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-4429-9

  • Online ISBN: 978-3-7091-4427-5

  • eBook Packages: Springer Book Archive

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