Summary
Research to date indicates that the human pineal gland synthesizes and secretes hormones which probably influence the functioning of the neuro-endocrine axis. There is no basis for the idea that the human pineal becomes less functional with age, or as it becomes calcified.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Giarman, N. J., Freedman, D. X., Picard-Ami, L.: Serotonin content of the pineal gland of man and monkey. Nature 186, 480–481 (1960).
Heubner, O.: Tumor der Glandula pinealis. Deut. Med. Wschr. 24, 214–215 (1898).
Kitay, J. I.: Pineal lesions and precocious puberty: A review. J. Clin. Endocr. 14, 622–625 (1954).
Lukaszyk, A., Reiter, R. J.: Histophysiological evidence for the secretion of Polypeptides by the pineal gland. Amer. J. Anat. 143, 451–464 (1975).
Lynch, H. J., Wurtman, R. J., Moskowitz, M. A., Archer, M. C., Ho, M. H.: Daily rhythm in human urinary melatonin. Science 187, 169–171 (1975).
Obrador, S., Soto, M., Gutierrez-Diaz, J. A.: Surgical management of tumors of the pineal region. Acta Neurochir. 34, 159–171 (1976).
Pelham, R. W., Vaughan, G. M., Sandock, K. L., Vaughan, M. K.: Twenty-four-hour cycle of a melatonin-like substance in the plasma of human males. J. Clin. Endocr. Metab. 37, 341–344 (1973).
Suzuki, J., Iwabuchi, T.: Surgical removal of pineal tumors (pinealomas and teratomas). J. Neurosurg. 23, 565–571 (1965).
Wilde, E., Frauchiger, E.: Modifications histologiques de l’épiphyse humaine pendant l’enfance, Page et le vieillissement. Progr. Brain Res. 10, 218 to 231 (1965).
Wurtman, R. J., Axelrod, J., Barchas, J. D.: Age and enzyme activity in the pineal gland. J. Clin. Endocr. 24, 299–301 (1964).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Springer-Verlag Wien
About this paper
Cite this paper
Reiter, R.J. (1978). Evidence for an Endocrine Function of the Human Pineal Gland. In: Nir, I., Reiter, R.J., Wurtman, R.J. (eds) The Pineal Gland. Journal of Neural Transmission, vol 13. Springer, Vienna. https://doi.org/10.1007/978-3-7091-4427-5_18
Download citation
DOI: https://doi.org/10.1007/978-3-7091-4427-5_18
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-4429-9
Online ISBN: 978-3-7091-4427-5
eBook Packages: Springer Book Archive