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Giant Cell Tumor

Giant Cell Tumor of Bone, Osteoclastoma

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Bone and Soft Tissue Tumors

Abstract

Giant cell tumor of bone is defined as an intramedullary bone tumor, with a specific predilection for age and location, composed of mononucleated cells and osteoclast-like multi-nucleated giant cells, and having a variable and unpredictable potential for growth1. The giant cell tumor usually behaves as a benign tumor, but has a significant tendency to recur locally and, rarely, may produce pulmonary metastases. These have the same histological features as the primary tumor and are frequently curable. Rarely, a giant cell tumor may transform into a high-grade sarcoma.

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Giant cell tumor

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Campanacci, M. (1999). Giant Cell Tumor. In: Bone and Soft Tissue Tumors. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3846-5_4

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