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Alzheimer’s Disease. Epidemiology, Neuropathology, Neurochemistry, and Clinics pp 565–574Cite as

Long term treatment of SDAT patients with pyritinol

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Summary

A group of 26 patients with the clinical diagnosis of Senile Dementia of Alzheimer’s type (SDAT) was randomly assigned in a double blind cross-over trial of pyritinol versus placebo. Psychiatric and neurological examination, psychometric testing and regional cerebral blood flow measurements were used to assess the effects of medication. Pyritinol had a beneficial effect on cognitive performance which was sustained during the long term follow up of one year.

Keywords

  • Word Pair
  • Regional Cerebral Blood Flow
  • Target Sentence
  • Demented Patient
  • Soft Neurological Sign

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Author information

Authors and Affiliations

  1. Department of Neurology, University of Zagreb Medical School, Yugoslavia

    Dr. S. Knezevic

  2. Memory Center of the University Hospital Centre, Zagreb, Yugoslavia

    Z. Mubrin

  3. Washington College, Chestertown, Maryland, USA

    G. Spilich

  4. Department of Psychiatry, University Hospital Centre, Zagreb, Yugoslavia

    G. Vucinic

  5. Institute of Psychology, University of Technology, Darmstadt, Federal Republic of Germany

    W. Wannenmacher

Authors
  1. Dr. S. Knezevic
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  2. Z. Mubrin
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  3. G. Spilich
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  4. G. Vucinic
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  5. W. Wannenmacher
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Editor information

Editors and Affiliations

  1. Department of Psychiatry, University of Würzburg, Würzburg, Federal Republic of Germany

    Prof. Dr. Konrad Maurer, Prof. Dr. Peter Riederer & Prof. Dr. Helmut Beckmann,  & 

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© 1990 Springer-Verlag Wien

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Knezevic, S., Mubrin, Z., Spilich, G., Vucinic, G., Wannenmacher, W. (1990). Long term treatment of SDAT patients with pyritinol. In: Maurer, K., Riederer, P., Beckmann, H. (eds) Alzheimer’s Disease. Epidemiology, Neuropathology, Neurochemistry, and Clinics. Key Topics in Brain Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3396-5_64

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  • DOI: https://doi.org/10.1007/978-3-7091-3396-5_64

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-82197-8

  • Online ISBN: 978-3-7091-3396-5

  • eBook Packages: Springer Book Archive